Abstract
The number of coronavirus disease 2019 (COVID-19) infection cases has been increasing globally, including in Indonesia. Definitive therapy for COVID-19 has not yet been found; hence, repurposed drugs for COVID-19 have been considered and have been practiced by several researchers in the world. This literature review investigates the action of xanthine oxidase as a component of the biomolecular pathway against severe acute respiratory syndrome-related coronavirus-2, the cause of COVID-19, and describes the mechanism and potential of uric acid drugs (allopurinol and febuxostat) as prophylaxis and curative therapy for COVID-19.
Original language | English |
---|---|
Pages (from-to) | 75-80 |
Number of pages | 6 |
Journal | Medical Journal of Indonesia |
Volume | 30 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2021 |
Keywords
- COVID-19
- Free radicals
- Uric acid
- Xanthine oxidase