TY - JOUR
T1 - Water absorption of chitosan, collagen, and chitosan/collagen blend membranes exposed to gamma-ray irradiation
AU - Lukitowati, Fajar
AU - Indrani, Decky Joesiana
N1 - Funding Information:
The authors are grateful to the Department of Research and Technology and Higher Education of Indonesia, for the grant awarded for this study. The authors appreciate Darmawan Darwis of the Radiation Processing Division, Centre of Isotope Application and Radiation, National Nuclear Energy Agency of Indonesia, and Neil Trout of the University of South Australia, for their valuable discussions. The irradiation process was provided by the Gamma-ray Irradiator Plant of the National Nuclear Energy Agency of Indonesia.
Publisher Copyright:
© 2018, Iranian Association of Pharmaceutical Scientists. All rights reserved.
PY - 2018
Y1 - 2018
N2 - This study investigated the water absorption of chitosan, collagen, and chitosan/collagen blend membranes exposed to gamma-ray irradiation. These membranes were produced via the solvent evaporation method. All membranes then underwent irradiation at 15 or 25 kGy gamma-ray doses, while membranes without irradiation were used as controls. After immersing the membranes in distilled water for up to 180 min, water absorption was determined by calculating the percentage weight increase. The results demonstrated some changes in the water absorption curves with differing membranes and irradiation doses. However, after 60 min, all of the water absorption curves plateaued. With respect to membrane type, the chitosan membranes exhibited the highest water absorption; the blend displayed the lowest; and also the collagen was in the mid range. With the use of higher radiation doses, the chitosan membranes displayed lower water absorption, which was also true of the blend but not collagen membranes. To conclude, the water absorption of chitosan, collagen, and chitosan/collagen blend membranes with and without gamma-ray irradiation initially increased steadily and then plateaued. The water absorption values of the irradiated blend membranes were the lowest; however, the values were relatively steady.
AB - This study investigated the water absorption of chitosan, collagen, and chitosan/collagen blend membranes exposed to gamma-ray irradiation. These membranes were produced via the solvent evaporation method. All membranes then underwent irradiation at 15 or 25 kGy gamma-ray doses, while membranes without irradiation were used as controls. After immersing the membranes in distilled water for up to 180 min, water absorption was determined by calculating the percentage weight increase. The results demonstrated some changes in the water absorption curves with differing membranes and irradiation doses. However, after 60 min, all of the water absorption curves plateaued. With respect to membrane type, the chitosan membranes exhibited the highest water absorption; the blend displayed the lowest; and also the collagen was in the mid range. With the use of higher radiation doses, the chitosan membranes displayed lower water absorption, which was also true of the blend but not collagen membranes. To conclude, the water absorption of chitosan, collagen, and chitosan/collagen blend membranes with and without gamma-ray irradiation initially increased steadily and then plateaued. The water absorption values of the irradiated blend membranes were the lowest; however, the values were relatively steady.
KW - Chitosan
KW - Collagen
KW - Gamma-ray
KW - Irradiation
KW - Water absorption
UR - http://www.scopus.com/inward/record.url?scp=85055032480&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85055032480
VL - 14
SP - 57
EP - 66
JO - Iranian Journal of Pharmaceutical Sciences
JF - Iranian Journal of Pharmaceutical Sciences
SN - 1735-2444
IS - 1
ER -