TY - JOUR
T1 - VDAC2 (porin-2) expression pattern and localization in the bovine testis
AU - Hinsch, Klaus Dieter
AU - Asmarinah, null
AU - Hinsch, Elvira
AU - Konrad, Lutz
PY - 2001/4/16
Y1 - 2001/4/16
N2 - In this study, sequencing of voltage-dependent anion channel 2 (VDAC2, porin-2) cDNA from bovine testis is reported. High identity to the murine, rabbit, and human subtypes at both the nucleotide and amino acid levels is demonstrated. mRNA analysis revealed expression of VDAC2 in bovine testis, whereas high levels of VDAC2 proteins were found in late spermatocytes, spermatids, and spermatozoa. In contrast, VDAC1 (porin-1) is exclusively localized in Sertoli cells. The possible role of testicular VDAC2 in providing energy metabolites and in germ cell apoptosis is discussed.
AB - In this study, sequencing of voltage-dependent anion channel 2 (VDAC2, porin-2) cDNA from bovine testis is reported. High identity to the murine, rabbit, and human subtypes at both the nucleotide and amino acid levels is demonstrated. mRNA analysis revealed expression of VDAC2 in bovine testis, whereas high levels of VDAC2 proteins were found in late spermatocytes, spermatids, and spermatozoa. In contrast, VDAC1 (porin-1) is exclusively localized in Sertoli cells. The possible role of testicular VDAC2 in providing energy metabolites and in germ cell apoptosis is discussed.
KW - Gene expression
KW - Spermatocyte
KW - Spermatozoon
KW - Voltage anion dependent channel 1
KW - Voltage anion dependent channel 2
UR - http://www.scopus.com/inward/record.url?scp=0035897190&partnerID=8YFLogxK
U2 - 10.1016/S0167-4781(01)00199-3
DO - 10.1016/S0167-4781(01)00199-3
M3 - Article
C2 - 11311949
AN - SCOPUS:0035897190
VL - 1518
SP - 329
EP - 333
JO - Biochimica et Biophysica Acta - Gene Structure and Expression
JF - Biochimica et Biophysica Acta - Gene Structure and Expression
SN - 0167-4781
IS - 3
ER -