Validity and reliability of the NEI VFQ-25 questionnaire in Indonesian leprosy patients

Tri Rahayu, Sri Linuwih Menaldi, Yunia Irawati, Gitalisa Andayani Adriono, Athira Presialia, Melinda Harini, Dewi Friska

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Background: The National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) is one of the most frequently used questionnaires to assess visual function. However, its validity and reliability have not been documented in specific context of use in leprosy patients. Objectives: To provide additional support to the reliability and validity of the NEI VFQ-25 in leprosy patients. Methods: The reliability was assessed using internal consistency analysis (Cronbach's α formula). For validity assessment, item analysis was conducted by calculating the coefficient of corrected item-total correlation. Results: The result showed all items included in the analysis were considered valid, as the coefficient was >0.3. Internal consistency reliability (calculation of all the questions taken together), the Cronbach's α of the instrument was 0.934 and 0.937. Due to low socioeconomic and low educational status, the majority of the patients have no vehicles nor can drive, therefore, there is a high missing rate of ‘Driving’ subscale. Conclusion: The NEI VFQ-25 is a reliable and valid instrument, and can be used to assess vision-related quality of life in Indonesian leprosy patients.

Original languageEnglish
Article number101039
JournalClinical Epidemiology and Global Health
Publication statusPublished - 1 May 2022


  • Leprosy
  • NEI VFQ-25
  • Reliability
  • Validity


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