This is the second paper of three papers reported the results of Phase II Study with single implant contraceptive releasing 3-ketodesogestrel (Implant). This paper reports the analysis of the menstrual diary records of200 women who participated in the above-mentioned study. The analysis was based on WHO reference period. The patterns show the highest of the mean member of bleeding-spotting days (26.7 days) during the first reference period which then decrease with time. The bleeding-spotting episodes are relatively constant (2.9 episodes) through the study. Ammenorrhoea was experienced by 7.6-12.4% of the subjects during the first two-year. A gradual decrease occurred in year-3 and year-4. Incidence of infrequent, frequent, and prolonged bleeding were diminished with time.
- Bleeding patterns
- Implant contraceptive