Using next-generation sequencing (NGS) to examine oral squamous cell carcinoma

Muhammad Garry Syahrizal Hanafi; Elza Ibrahim Auerkari

doi:10.1063/5.0047276

Using next-generation sequencing (NGS) to examine oral squamous cell carcinoma

Muhammad Garry Syahrizal Hanafi, Elza Ibrahim Auerkari

Department of Oral Biology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Oral Squamous Cell Carcinoma (OSCC) is the most common type of carcinoma cancer in the oral cavity. About 50% of all cases of Head and Neck Squamous Cell Carcinoma are OSCCs. Molecular identification needs to be done in cases of OSCC because the 5-year life expectancy or Disease-Specific Survival (DSS) of this cancer is low. The Next-Generation Sequencing (NGS) method is a solution to make molecular identification more effective and efficient than the previous method. Based on several studies using NGS to sequence OSCC, it is found that this method is reliable, has high throughput, able to evaluate genetic relationships more precisely and accurately, and requires faster time and cost more efficient when compared with conventional methods. In conclusion, the usage of NGS is highly recommended, in order to swiftly diagnose the particular cause of this cancer. This, in turn, will give optimal intervention for patients with OSCC, increasing their life expectancy.

Original language	English
Title of host publication	5th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
Subtitle of host publication	Proceedings of the 5th International Symposium of Biomedical Engineering, ISBE 2020
Editors	Kenny Lischer, Sugeng Supriadi, Siti Fauziyah Rahman, Yudan Whulanza
Publisher	American Institute of Physics Inc.
ISBN (Electronic)	9780735440869
DOIs	https://doi.org/10.1063/5.0047276
Publication status	Published - 23 Mar 2021
Event	5th International Symposium of Biomedical Engineering, ISBE 2020 - Depok, Virtual, Indonesia Duration: 28 Jul 2020 → 29 Jul 2020

Publication series

Name	AIP Conference Proceedings
Volume	2344
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	5th International Symposium of Biomedical Engineering, ISBE 2020
Country/Territory	Indonesia
City	Depok, Virtual
Period	28/07/20 → 29/07/20

Keywords

Molecular Identification
Next-Generation Sequencing (NGS)
Oral Squamous Cell Carcinoma

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1063/5.0047276

Cite this

Hanafi, M. G. S., & Auerkari, E. I. (2021). Using next-generation sequencing (NGS) to examine oral squamous cell carcinoma. In K. Lischer, S. Supriadi, S. F. Rahman, & Y. Whulanza (Eds.), 5th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the 5th International Symposium of Biomedical Engineering, ISBE 2020 Article 050009 (AIP Conference Proceedings; Vol. 2344). American Institute of Physics Inc.. https://doi.org/10.1063/5.0047276

Hanafi, Muhammad Garry Syahrizal ; Auerkari, Elza Ibrahim. / Using next-generation sequencing (NGS) to examine oral squamous cell carcinoma. 5th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the 5th International Symposium of Biomedical Engineering, ISBE 2020. editor / Kenny Lischer ; Sugeng Supriadi ; Siti Fauziyah Rahman ; Yudan Whulanza. American Institute of Physics Inc., 2021. (AIP Conference Proceedings).

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title = "Using next-generation sequencing (NGS) to examine oral squamous cell carcinoma",

abstract = "Oral Squamous Cell Carcinoma (OSCC) is the most common type of carcinoma cancer in the oral cavity. About 50% of all cases of Head and Neck Squamous Cell Carcinoma are OSCCs. Molecular identification needs to be done in cases of OSCC because the 5-year life expectancy or Disease-Specific Survival (DSS) of this cancer is low. The Next-Generation Sequencing (NGS) method is a solution to make molecular identification more effective and efficient than the previous method. Based on several studies using NGS to sequence OSCC, it is found that this method is reliable, has high throughput, able to evaluate genetic relationships more precisely and accurately, and requires faster time and cost more efficient when compared with conventional methods. In conclusion, the usage of NGS is highly recommended, in order to swiftly diagnose the particular cause of this cancer. This, in turn, will give optimal intervention for patients with OSCC, increasing their life expectancy.",

keywords = "Molecular Identification, Next-Generation Sequencing (NGS), Oral Squamous Cell Carcinoma",

author = "Hanafi, {Muhammad Garry Syahrizal} and Auerkari, {Elza Ibrahim}",

note = "Funding Information: The authors wish to gratefully acknowledge financial support from the Universitas Indonesia to EIA. Publisher Copyright: {\textcopyright} 2021 Author(s).; 5th International Symposium of Biomedical Engineering, ISBE 2020 ; Conference date: 28-07-2020 Through 29-07-2020",

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doi = "10.1063/5.0047276",

language = "English",

series = "AIP Conference Proceedings",

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Hanafi, MGS & Auerkari, EI 2021, Using next-generation sequencing (NGS) to examine oral squamous cell carcinoma. in K Lischer, S Supriadi, SF Rahman & Y Whulanza (eds), 5th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the 5th International Symposium of Biomedical Engineering, ISBE 2020., 050009, AIP Conference Proceedings, vol. 2344, American Institute of Physics Inc., 5th International Symposium of Biomedical Engineering, ISBE 2020, Depok, Virtual, Indonesia, 28/07/20. https://doi.org/10.1063/5.0047276

Using next-generation sequencing (NGS) to examine oral squamous cell carcinoma. / Hanafi, Muhammad Garry Syahrizal; Auerkari, Elza Ibrahim.
5th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the 5th International Symposium of Biomedical Engineering, ISBE 2020. ed. / Kenny Lischer; Sugeng Supriadi; Siti Fauziyah Rahman; Yudan Whulanza. American Institute of Physics Inc., 2021. 050009 (AIP Conference Proceedings; Vol. 2344).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Using next-generation sequencing (NGS) to examine oral squamous cell carcinoma

AU - Hanafi, Muhammad Garry Syahrizal

AU - Auerkari, Elza Ibrahim

PY - 2021/3/23

Y1 - 2021/3/23

N2 - Oral Squamous Cell Carcinoma (OSCC) is the most common type of carcinoma cancer in the oral cavity. About 50% of all cases of Head and Neck Squamous Cell Carcinoma are OSCCs. Molecular identification needs to be done in cases of OSCC because the 5-year life expectancy or Disease-Specific Survival (DSS) of this cancer is low. The Next-Generation Sequencing (NGS) method is a solution to make molecular identification more effective and efficient than the previous method. Based on several studies using NGS to sequence OSCC, it is found that this method is reliable, has high throughput, able to evaluate genetic relationships more precisely and accurately, and requires faster time and cost more efficient when compared with conventional methods. In conclusion, the usage of NGS is highly recommended, in order to swiftly diagnose the particular cause of this cancer. This, in turn, will give optimal intervention for patients with OSCC, increasing their life expectancy.

AB - Oral Squamous Cell Carcinoma (OSCC) is the most common type of carcinoma cancer in the oral cavity. About 50% of all cases of Head and Neck Squamous Cell Carcinoma are OSCCs. Molecular identification needs to be done in cases of OSCC because the 5-year life expectancy or Disease-Specific Survival (DSS) of this cancer is low. The Next-Generation Sequencing (NGS) method is a solution to make molecular identification more effective and efficient than the previous method. Based on several studies using NGS to sequence OSCC, it is found that this method is reliable, has high throughput, able to evaluate genetic relationships more precisely and accurately, and requires faster time and cost more efficient when compared with conventional methods. In conclusion, the usage of NGS is highly recommended, in order to swiftly diagnose the particular cause of this cancer. This, in turn, will give optimal intervention for patients with OSCC, increasing their life expectancy.

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KW - Next-Generation Sequencing (NGS)

KW - Oral Squamous Cell Carcinoma

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BT - 5th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices

A2 - Lischer, Kenny

A2 - Supriadi, Sugeng

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PB - American Institute of Physics Inc.

T2 - 5th International Symposium of Biomedical Engineering, ISBE 2020

Y2 - 28 July 2020 through 29 July 2020

ER -

Hanafi MGS, Auerkari EI. Using next-generation sequencing (NGS) to examine oral squamous cell carcinoma. In Lischer K, Supriadi S, Rahman SF, Whulanza Y, editors, 5th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the 5th International Symposium of Biomedical Engineering, ISBE 2020. American Institute of Physics Inc. 2021. 050009. (AIP Conference Proceedings). doi: 10.1063/5.0047276

Using next-generation sequencing (NGS) to examine oral squamous cell carcinoma

Abstract

Publication series

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Keywords

UN SDGs

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