Use of a DNA probe to detect Salmonella typhi in the blood of patients with typhoid fever

F. A. Rubin, P. D. McWhirter, N. H. Punjabi, E. Lane, Pratiwi Pudjilestari Sudarmono, S. P. Pulungsih, M. Lesmana, S. Kumala, D. J. Kopecko, S. L. Hoffman

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

A DNA probe was used to detect Salmonella typhi from blood samples from 14 of 33 patients with culture-confirmed typhoid fever, using the equivalent of 2.5 ml of blood. In contrast, S. typhi was detected in 17 of the same 33 patients by culture of 8 ml of blood. The probe hybridized to blood samples of 4 of 47 patients from whom S. typhi was not isolated.

Original languageEnglish
Pages (from-to)1112-1114
Number of pages3
JournalJournal of Clinical Microbiology
Volume27
Issue number5
Publication statusPublished - 1 Jan 1989

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