Underutilization of anticoagulant for venous thromboembolism prophylaxis in three hospitals in Jakarta

Tubagus Djumhana Atmakusuma, Karmel Lindow Tambunan, Lugyanti Sukrisman, Shufrie Effendi, Andhika Rachman, Arini Setiawati, Ikhwan Rinaldi, Nadia A. Mulansari, Wulyo Rajabto, Sally Aman Nasution, Muhadi, Tiara Aninditha, Rudyanto Sedono, Adhrie Sugiarto, Ceva Wijaksono, Diana Paramitha, Nyoto W. Astoro, Intan R. Nasution

Research output: Contribution to journalArticlepeer-review

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Abstract

AIM: to assess the current use of anticoagulants and implementation of International Guidelines in venous thromboembolism (VTE) prophylaxis in hospitalized patients with acute medical illnesses in Jakarta, Indonesia.

METHODS: a multicenter, prospective, disease registry, recruiting patients diagnosed as acutely ill medical diseases and other medical conditions at risk of VTE, with in-hospital immobilization for at least 3 days.

RESULTS: of 401 patients, 46.9% received anticoagulants which included unfractionated heparin (64.4%), fondaparinux (11.7%), enoxaparin (9.6%), warfarin (3.7%), and combination of anticoagulants (10.6%). VTE prophylaxis using physical and mechanical method was used in 81.3% of patients, either as a single modality or in combination with anticoagulants. During hospitalization, VTE were found in 3.2% patients; 10 patients (2.5%) had lower limb events and 3 patients (0.75%) had a suspected pulmonary embolism. The main reference international guidelines used were AHA/ASA 2007 (47.4%), followed by ACCP 2008 (21.7%).

CONCLUSION: the study showed underutilization of prophylaxis anticoagulants in which mechanical thromboprophylaxis either alone or combination with anticoagulants was the most commonly used. Unfractionated heparin was the preferable choice. The most commonly used guideline was AHA/ASA 2007. VTE thromboprophylaxis in medically ill patients needs to be encouraged.

Original languageEnglish
Pages (from-to)136-145
Number of pages10
JournalActa medica Indonesiana
Volume47
Issue number2
Publication statusPublished - 1 Apr 2015

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