Twiddler’s syndrome in patient with single chamber pacemaker

Muhammad Munawar, Ingrid Pardede, Dian Andina Munawar, Jimmy Pambudi

Research output: Contribution to journalArticlepeer-review


Twiddler’s syndrome is a well-known complication of pacemaker treatment. This syndrome is characterized by coiling of the pacemaker lead due to the rotation of pacemaker generator on its long axis. Lead damage could cause lead facture or insulation leakage. The syndrome is also responsible for lead dislodgment, diaphragmatic stimulation, twitching upper arm due to plexus brachial nerve stimulation and loss of capture. Understanding risk factors and preventive measurement is very important. In this case report we present an 84 year-old patient who managed to rotate his single chamber pacemaker generator unintentionally following implantation in which the syndrome occurred within 2 months causing insulation leakage and battery depletion. For the best of our knowledge, this is the first report of twiddler’s syndrome in Indonesia.

Original languageEnglish
Pages (from-to)295-297
Number of pages3
JournalMedical Journal of Indonesia
Issue number4
Publication statusPublished - Nov 2011


  • Lead damage
  • Long axis rotation
  • Pacemaker
  • Twiddler’s syndrome


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