Treatment Adherence and Incidence of Coronary Heart Diseasein Type 2 Diabetes Mellitus Patients

Ahmad Sahlan Baniu, Rani Sauriasari, Woro Riyadina, Pradana Soewondo

Research output: Contribution to journalArticlepeer-review


Previous studies showed that uncontrolled blood sugar and long-term use of several types of antidiabetic could increase the risk of coronary heart disease(CHD). This study aimed to compare the incidence of CHD in type 2 diabetes mellitus (T2DM) patients showing treatment adherence and non-adherence behavior over four years. This was a retrospective cohort study with data sets obtained from the Bogor Cohort Study of Non-Communicable Disease RiskFactors. All study subjects were not diagnosed with CHD at the beginning of the study. The sample was divided into two groups; one had adhered to treatmentfrom health centers and followed the treatment instructions (adherent group), while the other had not followed the treatment instructions (non-adherent group).Of 5,690 subjects, 276 were eligible for this study (84 in the adherent and 192 in the non-adherent group). The incidence of CHD in the non-adherent groupwas 2.3% higher than in the adherent group (p-value = 0.564) and had a 1.7 times greater risk of developing CHD, but not statistically significant (adjustedHR = 1.739; 95% CI = 0.673-4.490). The non-adherent T2DM patients had a greater risk of developing CHD than adherent T2DM patients.

Original languageEnglish
Pages (from-to)98-104
Number of pages7
Issue number2
Publication statusPublished - May 2022


  • coronary heart disease
  • diabetes mellitus
  • treatment adherence


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