Treatment Adherence and Incidence of Coronary Heart Diseasein Type 2 Diabetes Mellitus Patients

Ahmad Sahlan Baniu; Rani Sauriasari; Woro Riyadina; Pradana Soewondo

doi:10.21109/kesmas.v17i2.5453

Treatment Adherence and Incidence of Coronary Heart Diseasein Type 2 Diabetes Mellitus Patients

Ahmad Sahlan Baniu, Rani Sauriasari, Woro Riyadina, Pradana Soewondo

Research output: Contribution to journal › Article › peer-review

Abstract

Previous studies showed that uncontrolled blood sugar and long-term use of several types of antidiabetic could increase the risk of coronary heart disease(CHD). This study aimed to compare the incidence of CHD in type 2 diabetes mellitus (T2DM) patients showing treatment adherence and non-adherence behavior over four years. This was a retrospective cohort study with data sets obtained from the Bogor Cohort Study of Non-Communicable Disease RiskFactors. All study subjects were not diagnosed with CHD at the beginning of the study. The sample was divided into two groups; one had adhered to treatmentfrom health centers and followed the treatment instructions (adherent group), while the other had not followed the treatment instructions (non-adherent group).Of 5,690 subjects, 276 were eligible for this study (84 in the adherent and 192 in the non-adherent group). The incidence of CHD in the non-adherent groupwas 2.3% higher than in the adherent group (p-value = 0.564) and had a 1.7 times greater risk of developing CHD, but not statistically significant (adjustedHR = 1.739; 95% CI = 0.673-4.490). The non-adherent T2DM patients had a greater risk of developing CHD than adherent T2DM patients.

Original language	English
Pages (from-to)	98-104
Number of pages	7
Journal	Kesmas
Volume	17
Issue number	2
DOIs	https://doi.org/10.21109/kesmas.v17i2.5453
Publication status	Published - May 2022

Keywords

coronary heart disease
diabetes mellitus
treatment adherence

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.21109/kesmas.v17i2.5453

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title = "Treatment Adherence and Incidence of Coronary Heart Diseasein Type 2 Diabetes Mellitus Patients",

abstract = "Previous studies showed that uncontrolled blood sugar and long-term use of several types of antidiabetic could increase the risk of coronary heart disease(CHD). This study aimed to compare the incidence of CHD in type 2 diabetes mellitus (T2DM) patients showing treatment adherence and non-adherence behavior over four years. This was a retrospective cohort study with data sets obtained from the Bogor Cohort Study of Non-Communicable Disease RiskFactors. All study subjects were not diagnosed with CHD at the beginning of the study. The sample was divided into two groups; one had adhered to treatmentfrom health centers and followed the treatment instructions (adherent group), while the other had not followed the treatment instructions (non-adherent group).Of 5,690 subjects, 276 were eligible for this study (84 in the adherent and 192 in the non-adherent group). The incidence of CHD in the non-adherent groupwas 2.3% higher than in the adherent group (p-value = 0.564) and had a 1.7 times greater risk of developing CHD, but not statistically significant (adjustedHR = 1.739; 95% CI = 0.673-4.490). The non-adherent T2DM patients had a greater risk of developing CHD than adherent T2DM patients.",

keywords = "coronary heart disease, diabetes mellitus, treatment adherence",

author = "Baniu, {Ahmad Sahlan} and Rani Sauriasari and Woro Riyadina and Pradana Soewondo",

note = "Funding Information: The authors are grateful to the Ministry of Research and Technology or National Research and Innovation Agency of the Republic of Indonesia for giving financial support through PDUPT Grant No. NKB-064/UN2.RST/HKP.05.00/2021. This paper has been presented at the 16th APRU Multi-Hazards Symposium 2021 hosted by Disaster Risk Reduction Center Universitas Indonesia in collaboration with the Association of Pacific Rim Universities. Publisher Copyright: {\textcopyright} 2022 Seoul National University. All rights reserved.",

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doi = "10.21109/kesmas.v17i2.5453",

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AU - Baniu, Ahmad Sahlan

AU - Sauriasari, Rani

AU - Riyadina, Woro

AU - Soewondo, Pradana

N1 - Funding Information: The authors are grateful to the Ministry of Research and Technology or National Research and Innovation Agency of the Republic of Indonesia for giving financial support through PDUPT Grant No. NKB-064/UN2.RST/HKP.05.00/2021. This paper has been presented at the 16th APRU Multi-Hazards Symposium 2021 hosted by Disaster Risk Reduction Center Universitas Indonesia in collaboration with the Association of Pacific Rim Universities. Publisher Copyright: © 2022 Seoul National University. All rights reserved.

PY - 2022/5

Y1 - 2022/5

N2 - Previous studies showed that uncontrolled blood sugar and long-term use of several types of antidiabetic could increase the risk of coronary heart disease(CHD). This study aimed to compare the incidence of CHD in type 2 diabetes mellitus (T2DM) patients showing treatment adherence and non-adherence behavior over four years. This was a retrospective cohort study with data sets obtained from the Bogor Cohort Study of Non-Communicable Disease RiskFactors. All study subjects were not diagnosed with CHD at the beginning of the study. The sample was divided into two groups; one had adhered to treatmentfrom health centers and followed the treatment instructions (adherent group), while the other had not followed the treatment instructions (non-adherent group).Of 5,690 subjects, 276 were eligible for this study (84 in the adherent and 192 in the non-adherent group). The incidence of CHD in the non-adherent groupwas 2.3% higher than in the adherent group (p-value = 0.564) and had a 1.7 times greater risk of developing CHD, but not statistically significant (adjustedHR = 1.739; 95% CI = 0.673-4.490). The non-adherent T2DM patients had a greater risk of developing CHD than adherent T2DM patients.

AB - Previous studies showed that uncontrolled blood sugar and long-term use of several types of antidiabetic could increase the risk of coronary heart disease(CHD). This study aimed to compare the incidence of CHD in type 2 diabetes mellitus (T2DM) patients showing treatment adherence and non-adherence behavior over four years. This was a retrospective cohort study with data sets obtained from the Bogor Cohort Study of Non-Communicable Disease RiskFactors. All study subjects were not diagnosed with CHD at the beginning of the study. The sample was divided into two groups; one had adhered to treatmentfrom health centers and followed the treatment instructions (adherent group), while the other had not followed the treatment instructions (non-adherent group).Of 5,690 subjects, 276 were eligible for this study (84 in the adherent and 192 in the non-adherent group). The incidence of CHD in the non-adherent groupwas 2.3% higher than in the adherent group (p-value = 0.564) and had a 1.7 times greater risk of developing CHD, but not statistically significant (adjustedHR = 1.739; 95% CI = 0.673-4.490). The non-adherent T2DM patients had a greater risk of developing CHD than adherent T2DM patients.

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Treatment Adherence and Incidence of Coronary Heart Diseasein Type 2 Diabetes Mellitus Patients

Abstract

Keywords

UN SDGs

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