Transradial versus transfemoral access for female patients who underwent primary PCI in STEMI: Two years follow-up data from acute STEMI interventional registry

Sasko Kedev, Renan Sukmawan, Oliver Kalpak, Surya Dharma, Slobodan Antov, Jorgo Kostov, Hristo Pejkov, Igor Spiroski

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Background Female patients possess a higher risk for poorer outcome in ST segment elevation myocardial infarction (STEMI). There is possibility that transradial access (TRA) for primary percutaneous coronary intervention (PPCI) could provide better outcome than transfemoral access (TFA) in female patients with STEMI. Methods From 2008 to 2010, 418 female patients (out of 1808 patients) underwent PPCI for acute STEMI. The registry recruited all-comers patients with acute STEMI. Cardiac mortality, major bleeding, and overall MACE rates (composite of death, stroke, re MI and target vessel revascularization-TVR) after 2 years follow-up were compared between TRA and TFA. Results TRA for PPCI was performed in 261 patients and 157 underwent TFA PPCI. The 30-days, 1 year mortality and 2 year mortality rates were lower in TRA compared to TFA (6.9% vs.14.6%, p = 0.012, 8.8% vs. 15.3%, p = 0.045, and 9.2% vs. 16.6%, p = 0.027respectively). After 2 years follow-up, the overall MACE rates were similar (26.4% vs. 31.2%, p = 0.336). The overall major bleeding and major vascular access site bleeding were more favorable for TRA than TFA (4.4 vs. 14%, p < 0.001, and 2.7 vs. 10.8%, p < 0.001, respectively). Conclusion Transradial access for primary PCI in female patients provided better clinical outcomes with lower cardiac mortality and reduced major bleeding in comparison to TFA. There was no significant difference at 2 years MACE between TRA and TFA.

Original languageEnglish
Pages (from-to)S16-S20
JournalInternational Journal of Cardiology
Volume217
DOIs
Publication statusPublished - 1 Aug 2016

Keywords

  • Outcomes
  • ST-segment elevation myocardial infarction, primary PCI
  • Transradial access
  • Women

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