TY - JOUR
T1 - Touch Biopsy
T2 - A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected Patients
AU - Wahyuningsih, Retno
AU - Adawiyah, Robiatul
AU - Hoemardani, Aida S.D.
AU - Sjam, Ridhawati
AU - Yunihastuti, Evy
AU - Imran, Darma
AU - Miranda, Eliza
AU - Djauzi, Samsuridjal
AU - Tugiran, Mulyati
AU - Hariadi, Ariananda
AU - Surja, Sem Samuel
N1 - Funding Information:
RW received a research grant from Dana Ilmu Pengetahuan Indonesia/ Lembaga Pengelolaan Dana Pendidikan (DIPI/LPDP) with contract number MR/P017622/1, year 2017–2020.
Publisher Copyright:
© 2021, International Journal of Technology. All Rights Reserved.
PY - 2021
Y1 - 2021
N2 - Systemic fungal infection can disseminate to the skin and require prompt treatment, making early diagnosis very important. This study describes the use of a simple, quick touch biopsy method for the diagnosis of invasive mycoses in patients with AIDS with cutaneous manifestations. We identified fungal infections in 24 of the 29 investigated patients. Histoplasma capsulatum, Cryptococcus neoformans, Talaromyces artroroseus, Aspergillus flavus, Candida tropicalis, and Malassezia sp. were visualized directly in samples obtained from cutaneous lesions and confirmed by culture and molecular examination. The results suggested that touch biopsy is a simple, rapid method for the diagnosis of systemic mycoses with skin dissemination. It can be performed using simple tools and provides quick results, allowing for early intervention with appropriate antifungal therapy.
AB - Systemic fungal infection can disseminate to the skin and require prompt treatment, making early diagnosis very important. This study describes the use of a simple, quick touch biopsy method for the diagnosis of invasive mycoses in patients with AIDS with cutaneous manifestations. We identified fungal infections in 24 of the 29 investigated patients. Histoplasma capsulatum, Cryptococcus neoformans, Talaromyces artroroseus, Aspergillus flavus, Candida tropicalis, and Malassezia sp. were visualized directly in samples obtained from cutaneous lesions and confirmed by culture and molecular examination. The results suggested that touch biopsy is a simple, rapid method for the diagnosis of systemic mycoses with skin dissemination. It can be performed using simple tools and provides quick results, allowing for early intervention with appropriate antifungal therapy.
KW - Cutaneous dissemination
KW - Rapid diagnosis
KW - Systemic fungal infection
UR - http://www.scopus.com/inward/record.url?scp=85110251332&partnerID=8YFLogxK
U2 - 10.14716/ijtech.v12i2.4297
DO - 10.14716/ijtech.v12i2.4297
M3 - Article
AN - SCOPUS:85110251332
SN - 2086-9614
VL - 12
SP - 243
EP - 251
JO - International Journal of Technology
JF - International Journal of Technology
IS - 2
ER -
