Touch Biopsy: A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected Patients

Retno Wahyuningsih, Robiatul Adawiyah, Aida S.D. Hoemardani, Ridhawati Sjam, Evy Yunihastuti, Darma Imran, Eliza Miranda, Samsuridjal Djauzi, Mulyati Tugiran, Ariananda Hariadi, Sem Samuel Surja

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Systemic fungal infection can disseminate to the skin and require prompt treatment, making early diagnosis very important. This study describes the use of a simple, quick touch biopsy method for the diagnosis of invasive mycoses in patients with AIDS with cutaneous manifestations. We identified fungal infections in 24 of the 29 investigated patients. Histoplasma capsulatum, Cryptococcus neoformans, Talaromyces artroroseus, Aspergillus flavus, Candida tropicalis, and Malassezia sp. were visualized directly in samples obtained from cutaneous lesions and confirmed by culture and molecular examination. The results suggested that touch biopsy is a simple, rapid method for the diagnosis of systemic mycoses with skin dissemination. It can be performed using simple tools and provides quick results, allowing for early intervention with appropriate antifungal therapy.

Original languageEnglish
Pages (from-to)243-251
Number of pages9
JournalInternational Journal of Technology
Volume12
Issue number2
DOIs
Publication statusPublished - 2021

Keywords

  • Cutaneous dissemination
  • Rapid diagnosis
  • Systemic fungal infection

Fingerprint

Dive into the research topics of 'Touch Biopsy: A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected Patients'. Together they form a unique fingerprint.

Cite this