TY - JOUR
T1 - Total Phenolic Content of Natural Deep Eutectic Solvent (NADES) Extraction in Comfrey (Symphytum officinale)
AU - Syarifah, Andiri Niza
AU - Suryadi, Herman
AU - Mun'im, Abdul
PY - 2022/9
Y1 - 2022/9
N2 - Objective: The most common type of phytochemical is phenolic compounds. These compounds are mostly found in the plant kingdom, and extraction is one of the first and most important stages before any use. The green chemistry trend has encouraged the researcher to discover and generate innovative solvents in the extraction of phenolic compound (PC) as a strategy to toxic and potentially hazardous organic solvents. Natural Deep Eutectic Solvents (NADES) have recently been used as phenolic compound extraction solvents. The objective of this study is to determine the total phenolic contents of the NADES extract from comfrey (Symphytum officinale). Methods: This study used choline chloride-urea, choline chloride-glycerol and choline chloride-sucrose combination of NADES for extraction of phenolic compound in comfrey. The extraction was helped using Ultrasound Assisted Extraction (UAE). The extracted material was examined using a UV-Vis spectrophotometer. Results: The results showed that the total phenol of choline chloride-urea, chloride-glycerol and choline chloride-sucrose NADES comfrey extraction was 2.069, 1.566, and 1.906 mg GAE /gram of dry powder, respectively. Conclusion: Based on the result, it can be concluded type of NADES combination showed a different level of phenolic extraction. The best phenolic extraction was shown in the combination of choline chloride-urea.
AB - Objective: The most common type of phytochemical is phenolic compounds. These compounds are mostly found in the plant kingdom, and extraction is one of the first and most important stages before any use. The green chemistry trend has encouraged the researcher to discover and generate innovative solvents in the extraction of phenolic compound (PC) as a strategy to toxic and potentially hazardous organic solvents. Natural Deep Eutectic Solvents (NADES) have recently been used as phenolic compound extraction solvents. The objective of this study is to determine the total phenolic contents of the NADES extract from comfrey (Symphytum officinale). Methods: This study used choline chloride-urea, choline chloride-glycerol and choline chloride-sucrose combination of NADES for extraction of phenolic compound in comfrey. The extraction was helped using Ultrasound Assisted Extraction (UAE). The extracted material was examined using a UV-Vis spectrophotometer. Results: The results showed that the total phenol of choline chloride-urea, chloride-glycerol and choline chloride-sucrose NADES comfrey extraction was 2.069, 1.566, and 1.906 mg GAE /gram of dry powder, respectively. Conclusion: Based on the result, it can be concluded type of NADES combination showed a different level of phenolic extraction. The best phenolic extraction was shown in the combination of choline chloride-urea.
KW - Phenol
KW - Comfrey (Symphytum officinale)
KW - NADES
KW - Choline Chloride
UR - https://aisyah.journalpress.id/index.php/jika/article/view/7336
U2 - 10.30604/jika.v7i3.789
DO - 10.30604/jika.v7i3.789
M3 - Article
SN - 2502-4825
VL - 7
SP - 937
EP - 940
JO - Jurnal Aisyah : Jurnal Ilmu Kesehatan
JF - Jurnal Aisyah : Jurnal Ilmu Kesehatan
IS - 3
ER -