Many wireless devices in currently are used in close proximity to the human body. Interaction between the human limbs and electromagnetic (EM) waves unavoidably should be evaluated for wearable and implantable devices. This paper investigates the phenomenon of bioelectromagnetics on the human head model by modeling numerical tissue-mimicking model called phantoms includes a homogeneous phantom model and two-layer phantom in microwave frequencies. The head homogeneous phantom is a 2/3 muscle equivalent tissue while a two-layer phantom is skin and brain tissue layer. Dipole and loop antennas are applied in the proximity of the phantom models for studying the influence of the models on the antenna performances at 3.1 and 5.8 GHz. The results show that the dipole and loop antenna performances change when it is situated close to the phantom model in comparison with free space environment. Different tissue-mimicking model will affect differently the device performances due to energy absorption into the phantom model.