The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent

Khee Chung Hui; Nagaammai Dhanapalan; Apriliana Cahya Khayrani; Teguh Imanto; Nonni Soraya Sambudi

doi:10.5802/crchim.206

The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent

Khee Chung Hui, Nagaammai Dhanapalan, Apriliana Cahya Khayrani, Teguh Imanto, Nonni Soraya Sambudi

Department of Chemical Engineering

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Hydroxyapatite (HAp) was combined with amino-functionalized carbon quantum dots (CQDs) to enhance the optical and surface area properties of HAp. The loading of amino-functionalized CQDs could enhance the luminescence of HAp and its UV–Vis absorbance. Additionally, surface area of HAp could be increased from 84.16 to 129.94 m²/g by loading amino-functionalized CQDs. The drug release experiment was conducted using acetaminophen. The release happened slowly for amino-functionalized CQDs/HAp, with full release of acetaminophen being observed after 24 h. The enhanced luminescence composite shows high potential for the composite to be used for the controlled release of drugs.

Original language	English
Pages (from-to)	295-306
Number of pages	12
Journal	Comptes Rendus Chimie
Volume	25
DOIs	https://doi.org/10.5802/crchim.206
Publication status	Published - 2022

Keywords

Acetaminophen
Carbon quantum dots
Chitosan
Drug delivery
Hydroxyapatite

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10.5802/crchim.206

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title = "The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent",

abstract = "Hydroxyapatite (HAp) was combined with amino-functionalized carbon quantum dots (CQDs) to enhance the optical and surface area properties of HAp. The loading of amino-functionalized CQDs could enhance the luminescence of HAp and its UV–Vis absorbance. Additionally, surface area of HAp could be increased from 84.16 to 129.94 m2/g by loading amino-functionalized CQDs. The drug release experiment was conducted using acetaminophen. The release happened slowly for amino-functionalized CQDs/HAp, with full release of acetaminophen being observed after 24 h. The enhanced luminescence composite shows high potential for the composite to be used for the controlled release of drugs.",

keywords = "Acetaminophen, Carbon quantum dots, Chitosan, Drug delivery, Hydroxyapatite",

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doi = "10.5802/crchim.206",

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T1 - The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent

AU - Hui, Khee Chung

AU - Dhanapalan, Nagaammai

AU - Khayrani, Apriliana Cahya

AU - Imanto, Teguh

AU - Sambudi, Nonni Soraya

PY - 2022

Y1 - 2022

N2 - Hydroxyapatite (HAp) was combined with amino-functionalized carbon quantum dots (CQDs) to enhance the optical and surface area properties of HAp. The loading of amino-functionalized CQDs could enhance the luminescence of HAp and its UV–Vis absorbance. Additionally, surface area of HAp could be increased from 84.16 to 129.94 m2/g by loading amino-functionalized CQDs. The drug release experiment was conducted using acetaminophen. The release happened slowly for amino-functionalized CQDs/HAp, with full release of acetaminophen being observed after 24 h. The enhanced luminescence composite shows high potential for the composite to be used for the controlled release of drugs.

AB - Hydroxyapatite (HAp) was combined with amino-functionalized carbon quantum dots (CQDs) to enhance the optical and surface area properties of HAp. The loading of amino-functionalized CQDs could enhance the luminescence of HAp and its UV–Vis absorbance. Additionally, surface area of HAp could be increased from 84.16 to 129.94 m2/g by loading amino-functionalized CQDs. The drug release experiment was conducted using acetaminophen. The release happened slowly for amino-functionalized CQDs/HAp, with full release of acetaminophen being observed after 24 h. The enhanced luminescence composite shows high potential for the composite to be used for the controlled release of drugs.

KW - Acetaminophen

KW - Carbon quantum dots

KW - Chitosan

KW - Drug delivery

KW - Hydroxyapatite

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DO - 10.5802/crchim.206

M3 - Article

AN - SCOPUS:85175791642

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JO - Comptes Rendus Chimie

JF - Comptes Rendus Chimie

ER -

The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent

Abstract

Keywords

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