The study of diameter profile characteristics and narrowing of coronary arteries from computed tomography angiography images

A non-invasive method to predict the occurrence of stenosis isintroduced and used in this paper to analyze the diameter profile of coronary artery blood flow. In the arterial profile, differences in sex and age can affect the size of the coronary artery diameter. The coronary artery segmentation process uses threshold segmentation with a value of 130 HU on Computed Tomography Angiography (CTA) images. Arterial diameter profile was obtained from centerline extraction on image segmentation results with 64 male patients and 30 female patients divided into age ranges; 35 - 44 years, 45 - 54 years, 55 - 64 years, and 65 - 74 years. The average diameter measurement was carried out on the Right Coronary Artery (RCA) and Left Anterior Descending (LAD) vessels, each of 120 mm long, divided into 6 length categories. Based on gender, men have a larger coronary artery diameter than women for each category with a significance test on the RCA (p<0.05) and LAD (p>0.05). At a length of 120 mm, LAD provides a more drastic reduction in diameter than RCA with the difference in the average diameter of male LAD (0.35±0.12)/20 mm; female (0.33±0.16)/20 mm and male RCA (0.25±0.13)/20 mm; female (0.27±0.11)/20 mm. The outliers show the difference in the drastic profile reduction due to the narrowing and branching of the coronary arteries which are evaluated based on the 3D image of the arteries.