The salivary bone-specific alkaline phosphatase in relation to pubertal growth phase in Indonesian children

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Abstract

Objective: Objective of the study was to evaluate the level of salivary bone-specific alkaline phosphatase (BALP) during the pubertal growth phases in Indonesian children. Methods: The study conducted on 64 boys and 72 girls who were age group of 8-18 years old were randomly selected. Salivary BALP level were estimated using enzyme-linked immunosorbent assay commercial kits and pubertal growth phase were assessed using cervical vertebral maturation (CVM) method according to Baccetti. Mean salivary BALP was compared based on pubertal growth groups by analysis of variance test. Results: Test revealed no significant differences between groups with p=0.312. The highest mean of salivary BALP level was found in the prepeak pubertal growth phase (CVM Stage 1-2), and the lowest one was detected in the postpeak pubertal growth phase (CVM Stage 5-6). Conclusion: The using of salivary BALP as a biomarker for pubertal growth prediction is questionable.

Original languageEnglish
Pages (from-to)389-392
Number of pages4
JournalAsian Journal of Pharmaceutical and Clinical Research
Volume10
Issue number5
DOIs
Publication statusPublished - 2017

Keywords

  • Bone specific alkaline phosphatase
  • Cervical vertebral maturation
  • Pubertal growth
  • Salivary

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