The role of parathyroid hormone in alveolar bone resorption on postmenopausal women

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Postmenopausal women exhibit reduced bone mineralization, which causes bone resorption, including that of alveolar bone. Parathyroid hormone has been shown to play a role in alveolar bone resorption. Objective: This study aims to analyze relationships between parathyroid hormone and other factors that may contribute to alveolar bone resorption in postmenopausal women. Methods: This cross-sectional study included 82 postmenopausal women aged 50–74 years, who resided in Central and East Jakarta, Indonesia. Subjects' data were obtained through questionnaires, dental examinations, and blood collection for the examination of parathyroid hormone levels by enzyme-linked immunosorbent assay and using panoramic radiography to measure bone resorption. Results: Spearman correlation analysis showed a significant correlation between parathyroid hormone level (p = 0.005) and extent of alveolar bone resorption, but age (p = 0.292), menopausal duration (p = 0.244), and number of missing teeth (p = 0.517) were not significantly correlated with the extent of alveolar bone resorption. Conclusion: Various factors play a role in the mechanism of bone resorption, so knowing the role of each factor is expected to reduce the effects of alveolar bone resorption that occurs in postmenopause. Among the factors investigated in this study, the parathyroid hormone was the sole factor correlated with postmenopausal alveolar bone resorption.

Original languageEnglish
Pages (from-to)82-87
Number of pages6
JournalOpen Dentistry Journal
Volume14
Issue number1
DOIs
Publication statusPublished - 1 Jan 2020

Keywords

  • Age
  • Alveolar bone resorption
  • Panoramic radiography
  • Parathyroid hormone
  • Postmenopausal
  • Teeth

Fingerprint

Dive into the research topics of 'The role of parathyroid hormone in alveolar bone resorption on postmenopausal women'. Together they form a unique fingerprint.

Cite this