TY - JOUR
T1 - The Role of M2 Pyruvate Kinase in the Screening of Bowel Inflammation
AU - Ruswhandi, null
AU - Simadibrata, Marcellus
AU - Hasan, Irsan
PY - 2015
Y1 - 2015
N2 - Background: This is a study to determine if M2 Pyruvate Kinase (M2-PK) can be used to screen the presence of bowel inflammation. Method: The study design being used is diagnostic test. In this study, we recruited 76 participants and performed colonoscopy examination as a gold standard and faecal M2-PK as the examined procedure. Results: From the result of this study, we identified the important role of M2-PK to screen the presence of bowel inflammation with the cut-off point of 1.05 U/mL compared to colonoscopy as gold standard with the sensitivity of 86.2%, specificity 81.8%, positive predictive value 96.6%, and negative predictive value 50%. Conclusion: From the result of this study, we suggested M2-PK examination to screen bowel inflammation in patients with lower gastrointestinal tract problems.
AB - Background: This is a study to determine if M2 Pyruvate Kinase (M2-PK) can be used to screen the presence of bowel inflammation. Method: The study design being used is diagnostic test. In this study, we recruited 76 participants and performed colonoscopy examination as a gold standard and faecal M2-PK as the examined procedure. Results: From the result of this study, we identified the important role of M2-PK to screen the presence of bowel inflammation with the cut-off point of 1.05 U/mL compared to colonoscopy as gold standard with the sensitivity of 86.2%, specificity 81.8%, positive predictive value 96.6%, and negative predictive value 50%. Conclusion: From the result of this study, we suggested M2-PK examination to screen bowel inflammation in patients with lower gastrointestinal tract problems.
UR - http://ina-jghe.com/journal/index.php/jghe/article/view/471
U2 - 10.24871/161201522-25
DO - 10.24871/161201522-25
M3 - Article
SN - 1411-4801
VL - 16
SP - 22
EP - 25
JO - The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy
JF - The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy
IS - 1
ER -