The role of CYP2A6 genetic polymorphism in nicotine dependence and tobacco consumption among bataknese male smokers

Noni Novisari Soeroso, Rozaimah Zain-Hamid, Bintang Y.M. Sinaga, Ahmad Hamim Sadewa, Tamsil Syafiuddin, Elisna Syahruddin, Gino Tann, Erna Mutiara

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

AIM: This research aimed to analyse the relationship between CYP2A6 gene polymorphism with nicotine dependence and its relation to the number of cigarette consumption among Bataknese smokers. METHOD: This study was a cross-sectional study involving 140 research subjects in Medan, Indonesia. RESULTS: Nicotine dependence rates were found to be significantly associated with the number of cigarette consumption expressed in the Brinkman Index. CONCLUSION: The *1A wild-type alleles have a greater risk of high-very high dependence rate compared to the other variants.

Original languageEnglish
Pages (from-to)864-866
Number of pages3
JournalOpen Access Macedonian Journal of Medical Sciences
Volume6
Issue number5
DOIs
Publication statusPublished - 1 May 2018

Keywords

  • Bataknese
  • Brinkman index
  • Nicotine dependence
  • Polymorphism of CYP2A6 gene

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