The Potency of Carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) as a noncollagen protein analog to dentine remineralization

Atria Mya Kelani; Nilakesuma Djauharie; Ratna Meidyawati; Endang Suprastiwi; Rivanti Irmadela Devina

The Potency of Carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) as a noncollagen protein analog to dentine remineralization

Atria Mya Kelani, Nilakesuma Djauharie, Ratna Meidyawati, Endang Suprastiwi, Rivanti Irmadela Devina

Department of Conservative Dentistry

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) is a noncollagen protein analog material that may serve as a regulator of the intrafibrillar remineralization mechanism through the guided tissue remineralization (GTR) approach. Methods: Eight 3-mm depth demineralized cavities were divided into two groups: group 1 cavities were immediately filled with temporary restoration; while group 2 received CMC/ACP first and only then were filled with temporary restoration. All samples were immersed in phosphate buffered saline (PBS) and were stored in a 37 oC shaking incubator. Remineralization evaluation with scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX) was done on day seven. Results: In group 2, SEM images showed the presence of irregularity in dentinal tubules, and EDX analysis showed significantly increased calcium and phosphate levels in dentinal tubules. Conclusion: CMC/ACP has the potency to remineralize dentine.

Original language	English
Pages (from-to)	1258-1262
Number of pages	5
Journal	Journal of International Dental and Medical Research
Issue number	4
Publication status	Published - 1 Jan 2019

Keywords

CMC/ACP
Dentine
DMP 1
Noncollagen protein analogs
Remineralization

Cite this

@article{eb471ca7016d41bdb1fa30adb33c0d60,

title = "The Potency of Carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) as a noncollagen protein analog to dentine remineralization",

abstract = "Carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) is a noncollagen protein analog material that may serve as a regulator of the intrafibrillar remineralization mechanism through the guided tissue remineralization (GTR) approach. Methods: Eight 3-mm depth demineralized cavities were divided into two groups: group 1 cavities were immediately filled with temporary restoration; while group 2 received CMC/ACP first and only then were filled with temporary restoration. All samples were immersed in phosphate buffered saline (PBS) and were stored in a 37 oC shaking incubator. Remineralization evaluation with scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX) was done on day seven. Results: In group 2, SEM images showed the presence of irregularity in dentinal tubules, and EDX analysis showed significantly increased calcium and phosphate levels in dentinal tubules. Conclusion: CMC/ACP has the potency to remineralize dentine.",

keywords = "CMC/ACP, Dentine, DMP 1, Noncollagen protein analogs, Remineralization",

author = "Kelani, {Atria Mya} and Nilakesuma Djauharie and Ratna Meidyawati and Endang Suprastiwi and Devina, {Rivanti Irmadela}",

note = "Publisher Copyright: {\textcopyright} 2019 University of Dicle.",

year = "2019",

month = jan,

day = "1",

language = "English",

pages = "1258--1262",

journal = "Journal of International Dental and Medical Research",

issn = "1309-100X",

publisher = "Ektodermal Displazi Grubu",

number = "4",

}

TY - JOUR

T1 - The Potency of Carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) as a noncollagen protein analog to dentine remineralization

AU - Kelani, Atria Mya

AU - Djauharie, Nilakesuma

AU - Meidyawati, Ratna

AU - Suprastiwi, Endang

AU - Devina, Rivanti Irmadela

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) is a noncollagen protein analog material that may serve as a regulator of the intrafibrillar remineralization mechanism through the guided tissue remineralization (GTR) approach. Methods: Eight 3-mm depth demineralized cavities were divided into two groups: group 1 cavities were immediately filled with temporary restoration; while group 2 received CMC/ACP first and only then were filled with temporary restoration. All samples were immersed in phosphate buffered saline (PBS) and were stored in a 37 oC shaking incubator. Remineralization evaluation with scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX) was done on day seven. Results: In group 2, SEM images showed the presence of irregularity in dentinal tubules, and EDX analysis showed significantly increased calcium and phosphate levels in dentinal tubules. Conclusion: CMC/ACP has the potency to remineralize dentine.

AB - Carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) is a noncollagen protein analog material that may serve as a regulator of the intrafibrillar remineralization mechanism through the guided tissue remineralization (GTR) approach. Methods: Eight 3-mm depth demineralized cavities were divided into two groups: group 1 cavities were immediately filled with temporary restoration; while group 2 received CMC/ACP first and only then were filled with temporary restoration. All samples were immersed in phosphate buffered saline (PBS) and were stored in a 37 oC shaking incubator. Remineralization evaluation with scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX) was done on day seven. Results: In group 2, SEM images showed the presence of irregularity in dentinal tubules, and EDX analysis showed significantly increased calcium and phosphate levels in dentinal tubules. Conclusion: CMC/ACP has the potency to remineralize dentine.

KW - CMC/ACP

KW - Dentine

KW - DMP 1

KW - Noncollagen protein analogs

KW - Remineralization

UR - http://www.scopus.com/inward/record.url?scp=85081262704&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:85081262704

SN - 1309-100X

SP - 1258

EP - 1262

JO - Journal of International Dental and Medical Research

JF - Journal of International Dental and Medical Research

IS - 4

ER -

The Potency of Carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) as a noncollagen protein analog to dentine remineralization

Abstract

Keywords

Other files and links

Fingerprint

Cite this