The potency of active compound from mangrove fungal endophyte Emericella nidulans BPPTCC 6038 as bioinsecticide

Silva Abraham, Adi Basukriadi, Suyanto Pawiroharsono, Wellyzar Sjamsuridzal

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

Mangrove fungi are known as the sources of secondary metabolites of active compounds. In the search for novel, potent, fungi-derived bioactive compounds for bioinsecticide applications, crude ethyl acetate culture filtrate extract from Emericella nidulans BPPTCC 6038 was tested for toxic activity using brine shrimp lethality bioassay against Artemia salina larvae; insecticidal activity using indirect contact bioassay against neonate of Spodotera litura larvae; and acetylcholinesterase (AChE) inhibition activity by acethylcholinesterase inhibition assay. The results showed that the extract exhibited toxic activity against A. salina larvae, rated as highly toxic at 80 ppm; exhibited insecticidal activity against S. litura larvae, causing mortality by 66.67% at 5 mg; and acetylcholinesterase inhibition activity by 47.60% at 100 ppm. The fractionation on the E. nidulans BPPTCC 6038 extract produced seven fractions, and the best insecticidal activity against S. litura neonate larvae using feeding dietary bioassay was exhibited by the fraction no. 6, causing 98.33% larval mortality at 2500 ppm. The chemical characterization of the E. nidulans BPPTCC 6038 extracts using thin layer chromatography combined with several reagents showed that the extract contained triterpenoid, saponin and phenolic compounds, and the active fraction (fraction no. 6) from E. nidulans BPPTCC 6038 contained triterpenoid and saponin compounds. Thus, the extract of the E. nidulans BPPTCC 6038 might provide new bioactive compounds to be applied as potential bioinsecticides.

Original languageEnglish
Title of host publicationInternational Symposium on Current Progress in Mathematics and Sciences 2015, ISCPMS 2015
Subtitle of host publicationProceedings of the 1st International Symposium on Current Progress in Mathematics and Sciences
EditorsTerry Mart, Djoko Triyono
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735413764
DOIs
Publication statusPublished - 19 Apr 2016
Event1st International Symposium on Current Progress in Mathematics and Sciences, ISCPMS 2015 - Depok, Indonesia
Duration: 3 Nov 20154 Nov 2015

Publication series

NameAIP Conference Proceedings
Volume1729
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference1st International Symposium on Current Progress in Mathematics and Sciences, ISCPMS 2015
CountryIndonesia
CityDepok
Period3/11/154/11/15

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