THE PHYTOCHEMICAL SCREENING HEXANE AND METHANOL EXTRACT OF SINYO NAKAL (DURANTA REPENS)

Purwantiningsih Sugita, Rizki Amilia, Budi Arifin, Dyah utami cahyaning Rahayu, Hanhan Dianhar

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Phytochemicals are naturally present in every part of plants range from leaves, stem bark, and fruits to roots. The use of plant-based medicine is popular among individuals and communities in developing countries. This study evaluated that the phytochemical profile of Duranta repens fruits was collected from Jombang, East Java, Indonesia.

Methods: Air-dried D. repens fruits were macerated by n-hexane and methanol, a separate flask. n-Hexane extract, then underwent saponification to remove fat. Then, the unsaponifiable of n-hexane and methanol extract was tested through phytochemical screening, respectively.

Results: The methanol extract showed the presence of alkaloids, flavonoids, tannins, and steroids, but the unsaponifiable fraction only contained steroids. The unsaponifiable fraction was found to be a mixture of hydrocarbons ranging from C13-C20, fatty acids (palmitic and linoleic acid), squalene, and Vitamin E.

Conclusion: The phytochemical screening of the plant plays an important role for pharmaceutical studies especially discovering new potential drugs for the treatment of various diseases.
Original languageEnglish
Pages (from-to)196-200
JournalAsian Journal of Pharmaceutical and Clinical Research
Volume13
Issue number8
DOIs
Publication statusPublished - 2020

Keywords

  • Duranta repens
  • Unsaponifiable hexane fraction
  • Methanol extract

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