The new alkaloids from Antidesma cuspidatum M.A

Berna Elya, Roshamur C. Forestrania, Mat Ropi, Soleh Kosela, Khalijah Awang, Hanita Omar, A. Hamid A Hadi

Research output: Contribution to journalArticle

Abstract

Two new alkaloids, cuspidatin (1) and cuspidatinol (2), were isolated from Antidesma cuspidatum M.A. (Euphorbiaceae). The structures were determined by means of spectroscopic analysis (IR, MS, and NMR spectroscopy). The results of cytotoxicity evaluation showed that compounds 1 and 2 were inhibitory to L1210 cells, with IC50 values 8.41 and 6.36 μg/mL respectively.

Original languageEnglish
Pages (from-to)342-347
Number of pages6
JournalRecords of Natural Products
Volume8
Issue number4
Publication statusPublished - 1 Jan 2014

Keywords

  • Alkaloids
  • Antidesma cuspidatum M.A
  • Cytotoxic activity
  • Euphorbiaceae

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