The new alkaloids from Antidesma cuspidatum M.A

Berna Elya; Roshamur C. Forestrania; Mat Ropi; Soleh Kosela; Khalijah Awang; Hanita Omar; A. Hamid A Hadi

The new alkaloids from Antidesma cuspidatum M.A

Berna Elya, Roshamur C. Forestrania, Mat Ropi, Soleh Kosela, Khalijah Awang, Hanita Omar, A. Hamid A Hadi

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Two new alkaloids, cuspidatin (1) and cuspidatinol (2), were isolated from Antidesma cuspidatum M.A. (Euphorbiaceae). The structures were determined by means of spectroscopic analysis (IR, MS, and NMR spectroscopy). The results of cytotoxicity evaluation showed that compounds 1 and 2 were inhibitory to L1210 cells, with IC₅₀ values 8.41 and 6.36 μg/mL respectively.

Original language	English
Pages (from-to)	342-347
Number of pages	6
Journal	Records of Natural Products
Volume	8
Issue number	4
Publication status	Published - 2014

Keywords

Alkaloids
Antidesma cuspidatum M.A
Cytotoxic activity
Euphorbiaceae

Cite this

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abstract = "Two new alkaloids, cuspidatin (1) and cuspidatinol (2), were isolated from Antidesma cuspidatum M.A. (Euphorbiaceae). The structures were determined by means of spectroscopic analysis (IR, MS, and NMR spectroscopy). The results of cytotoxicity evaluation showed that compounds 1 and 2 were inhibitory to L1210 cells, with IC50 values 8.41 and 6.36 μg/mL respectively.",

keywords = "Alkaloids, Antidesma cuspidatum M.A, Cytotoxic activity, Euphorbiaceae",

author = "Berna Elya and Forestrania, {Roshamur C.} and Mat Ropi and Soleh Kosela and Khalijah Awang and Hanita Omar and Hadi, {A. Hamid A}",

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T1 - The new alkaloids from Antidesma cuspidatum M.A

AU - Elya, Berna

AU - Forestrania, Roshamur C.

AU - Ropi, Mat

AU - Kosela, Soleh

AU - Awang, Khalijah

AU - Omar, Hanita

AU - Hadi, A. Hamid A

PY - 2014

Y1 - 2014

N2 - Two new alkaloids, cuspidatin (1) and cuspidatinol (2), were isolated from Antidesma cuspidatum M.A. (Euphorbiaceae). The structures were determined by means of spectroscopic analysis (IR, MS, and NMR spectroscopy). The results of cytotoxicity evaluation showed that compounds 1 and 2 were inhibitory to L1210 cells, with IC50 values 8.41 and 6.36 μg/mL respectively.

AB - Two new alkaloids, cuspidatin (1) and cuspidatinol (2), were isolated from Antidesma cuspidatum M.A. (Euphorbiaceae). The structures were determined by means of spectroscopic analysis (IR, MS, and NMR spectroscopy). The results of cytotoxicity evaluation showed that compounds 1 and 2 were inhibitory to L1210 cells, with IC50 values 8.41 and 6.36 μg/mL respectively.

KW - Alkaloids

KW - Antidesma cuspidatum M.A

KW - Cytotoxic activity

KW - Euphorbiaceae

UR - http://www.scopus.com/inward/record.url?scp=84908223501&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84908223501

SN - 1307-6167

VL - 8

SP - 342

EP - 347

JO - Records of Natural Products

JF - Records of Natural Products

IS - 4

ER -

The new alkaloids from Antidesma cuspidatum M.A

Abstract

Keywords

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