TY - JOUR
T1 - The link between vitamin A dietary status and anaemia in pregnancy
T2 - A comparative cross-sectional study
AU - Tandaju, Jeremy Rafael
AU - Bardosono, Saptawati
AU - Dewi, Metta
N1 - Funding Information:
Source of Funding: This research was conducted with financial support from a PITTA (internationally indexed publication for Universitas Indonesia's student final assignment) grant provided by the Department of Research at Universitas Indonesia.
Publisher Copyright:
© 2021 Pakistan Medical Association. All rights reserved.
PY - 2021/2/1
Y1 - 2021/2/1
N2 - OBJECTIVE: Anaemia in pregnancy occurs mainly in the second and third trimesters. It is becoming more common among Indonesians and is associated with complications. Vitamin A assists in iron and cell metabolism but is unpopular during pregnancy. To assess the relationship between dietary status of vitamin A and anaemia in women in the third trimester of pregnancy. Methods: A pilot comparative cross-sectional study of 22 women with anaemia and 22 women without anaemia was conducted between August to October of 2018. Vitamin A dietary status was measured using a semi-quantitative food frequency questionnaire with a cut-off of 850 mcg/day deemed adequate. Anaemia status was assessed using a haematology analyser with a cut-off of 10.5 g/dL and values below the cut-off were considered anaemic. RESULTS: The difference in mean age between the anaemia and non-anaemia groups was not statistically significant. However, there was a clinical disparity in incidence of anaemia according to gestational age, with 55.2% at term gestational age and 40.0% at preterm gestational age. It was found that 38.6% of the initial subjects were anaemic and 81.8% did not have sufficient daily vitamin A. Despite its role in cell metabolism; there was no link between vitamin A dietary status and anaemia status. CONCLUSIONS: Vitamin A alone was unsuccessful in preventing anaemia in the third trimester. It is suggested, however, that it could be beneficial when combined with iron, folic acid and cobalamin.
AB - OBJECTIVE: Anaemia in pregnancy occurs mainly in the second and third trimesters. It is becoming more common among Indonesians and is associated with complications. Vitamin A assists in iron and cell metabolism but is unpopular during pregnancy. To assess the relationship between dietary status of vitamin A and anaemia in women in the third trimester of pregnancy. Methods: A pilot comparative cross-sectional study of 22 women with anaemia and 22 women without anaemia was conducted between August to October of 2018. Vitamin A dietary status was measured using a semi-quantitative food frequency questionnaire with a cut-off of 850 mcg/day deemed adequate. Anaemia status was assessed using a haematology analyser with a cut-off of 10.5 g/dL and values below the cut-off were considered anaemic. RESULTS: The difference in mean age between the anaemia and non-anaemia groups was not statistically significant. However, there was a clinical disparity in incidence of anaemia according to gestational age, with 55.2% at term gestational age and 40.0% at preterm gestational age. It was found that 38.6% of the initial subjects were anaemic and 81.8% did not have sufficient daily vitamin A. Despite its role in cell metabolism; there was no link between vitamin A dietary status and anaemia status. CONCLUSIONS: Vitamin A alone was unsuccessful in preventing anaemia in the third trimester. It is suggested, however, that it could be beneficial when combined with iron, folic acid and cobalamin.
KW - Anaemia, Vitamin A, Retinoid, Third trimester, Pregnancy.
UR - http://www.scopus.com/inward/record.url?scp=85103745177&partnerID=8YFLogxK
M3 - Article
C2 - 33785956
AN - SCOPUS:85103745177
SN - 0030-9982
VL - 71 2)
SP - S123-S128
JO - JPMA. The Journal of the Pakistan Medical Association
JF - JPMA. The Journal of the Pakistan Medical Association
IS - 2
ER -