TY - JOUR
T1 - The Isolation of myristicin from nutmeg oil by sequences distillation
AU - Sudradjat, Susana Elya
AU - Timotius, Kris Herawan
AU - Mun’im, Abdul
AU - Anwar, Effionora
N1 - Funding Information:
This study was supported by Directorate of Research and Community Service (DRPM) Universitas Indonesia via a grant “Hibah Publikasi In-ternasional Terindeks Untuk Tugas Akhir Mahasiswa Universitas Indonesia (Pitta)” 2017.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Background: Nutmeg oil is used in Asia as a traditional medicine for a stomach cramps, diarrhea, and insomnia. It’s quality need to be improved by increasing myristicin content. Objectives: This study aimed to increase the myristicin content of nutmeg oil by sequences distillations. Methods: Three different conditions of distillations were applied sequentially. The first, second and third distillation were at 1100C (0.2 bars), 1050C (1 bar), and 1450C (0.2 bars) respectively. Myristicin contents determined by gas chromatography-mass spectrometry (GC-MS). Results: the myristicin content of the original nutmeg oil, the first, the second, and the third distillation were 12.93%, 17.50%, 54.21%, and 83.45% respectively. The total yield of the final product resulted after the third distillation was 5.84% v/v from the original oil. Conclusion: The use of sequences distillation with a different condition can increase the myristicin content from the original nutmeg oil.
AB - Background: Nutmeg oil is used in Asia as a traditional medicine for a stomach cramps, diarrhea, and insomnia. It’s quality need to be improved by increasing myristicin content. Objectives: This study aimed to increase the myristicin content of nutmeg oil by sequences distillations. Methods: Three different conditions of distillations were applied sequentially. The first, second and third distillation were at 1100C (0.2 bars), 1050C (1 bar), and 1450C (0.2 bars) respectively. Myristicin contents determined by gas chromatography-mass spectrometry (GC-MS). Results: the myristicin content of the original nutmeg oil, the first, the second, and the third distillation were 12.93%, 17.50%, 54.21%, and 83.45% respectively. The total yield of the final product resulted after the third distillation was 5.84% v/v from the original oil. Conclusion: The use of sequences distillation with a different condition can increase the myristicin content from the original nutmeg oil.
KW - GC-MS
KW - Myristicin
KW - Nutmeg oil
KW - Sequences distillation
UR - http://www.scopus.com/inward/record.url?scp=85042522763&partnerID=8YFLogxK
U2 - 10.5530/jyp.2018.10.6
DO - 10.5530/jyp.2018.10.6
M3 - Article
AN - SCOPUS:85042522763
SN - 0975-1483
VL - 10
SP - 20
EP - 23
JO - Journal of Young Pharmacists
JF - Journal of Young Pharmacists
IS - 1
ER -
