The influence of smoking on IL-17 cytokine in chronic periodontitis patients

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8 Citations (Scopus)


Interleukin-17 is a cytokine derived from T cells. This cytokine has a role in beginning and continuing a pro-inflammatory sensitivity and the development of periodontal disease. To investigate the effect of IL-17 levels in the gingival crevicular fluid of smokers compared with the non-smokers with chronic periodontitis. GCF samples were taken from the deepest pocket affected by periodontal disease (attachment loss ≥ 3mm) from 14 subjects of smokers and 11 subjects of non-smokers. The examination of IL-17 levels using ELISA. There were no significant differences in total IL-17 levels in GCF between smokers and non-smokers with chronic periodontitis and there was no significant change in IL-17 levels in GCF related to the amount of cigarette consumption. Smoking did not significantly affect total levels of IL-17 in chronic periodontitis.

Original languageEnglish
Pages (from-to)199-202
Number of pages4
JournalJournal of International Dental and Medical Research
Issue number1
Publication statusPublished - 1 Jan 2019


  • Chronic periodontitis
  • GCF
  • IL-17
  • Smoking


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