This study aims to analyse the impact of social media use and content on the mental health of young people in Indonesia. This research uses a quantitative approach using an online questionnaire. There were 1,402 respondents who participated in this study. The collected data was analysed using a multiple linear regression method with a mediation relationship. The tool used to process the data was IBM SPSS version 25. This research shows that social media use, social media content, emotion regulation, perceived stress, and poor sleep affects depressive symptoms. The results of this study can help regulators and health service providers to provide better facilities for handling mental health cases, especially those due to the use and content of social media. The results of this study are expected to help social media developers develop features that provide a safe online environment for social media users.