The gastroesophageal reflux disease questionnaire in adolescents: What is the best cutoff score?

Dian Artanti, Badriul Hegar, Nastiti Kaswandani, Soedjatmiko, Yoga Devaera, Yvan Vandenplas, ARI PRAYITNO

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Background: A self-assessment questionnaire, the GERD-Questionnaire (GERD-Q) was used to determine the prevalence of GERD in adolescents, describe the related factors, and determine the impact on quality of life (QoL). Methods: The incidence of GERD was evaluated using the GERD-Q in adolescents aged 12-18 years. The Pediatric Gastroesophageal Reflux Disease Symptom Questionnaire and Quality of Life Questionnaire (PGSQ-A) for adolescents were additionally administered. Some factors considered related to GERD were also evaluated. Results: The 520 adolescents were included. The prevalence of suspected GERD, according to a GERD-Q cutoff score of ≥7 was 32.9%, and those drinking soda were 1.7 times more likely to have GERD (95% confidence interval, 1.3-2.2; p < 0.001). However, soda consumption was not a risk factor for development of GERD symptoms. Applying a cutoff score of ≥8, only 10.9% of the participants had a positive GERD score, but the association with soda consumption persisted. The median PGSQ-A score in subjects suspected of GERD was 8 (range 0-37) on weekends and 1 (range 0-17) during weekdays (p < 0.001) compared to those not suspected of GERD, with a median of 2 (range 0-27) during weekends and 0 (range 0-10) during weekdays. Heartburn, regurgitation, and extraesophageal symptoms correlated significantly with QoL (p < 0.001). Conclusion: The prevalence of suspected GERD in adolescents was 32.9% or 10.9%, depending on the cutoff score used. There was a statistically significant difference in PGSQ-A scores between the subjects suspected or not of GERD, indicating an impaired QoL.

Original languageEnglish
Pages (from-to)341-349
Number of pages9
JournalPediatric Gastroenterology, Hepatology and Nutrition
Issue number4
Publication statusPublished - 1 Jan 2019


  • Adolescent
  • Gastroesophageal reflux disease
  • Quality of life
  • Questionnaire


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