@inproceedings{8a408e00e2c4452c9dad644aaf253145,
title = "The experiment of magnesium ECAP miniplate as alternative biodegradable material (on male white New Zealand rabbits)",
abstract = "Study of biodegradations of Magnesium ECAP (Equal Channel Angular Pressing) miniplate in the osteosynthesis system has been used as a new material for plate and screw in oral and maxillofacial surgery. This miniplate and screw that were made of Magnesium ECAP were implanted in the femurs of New Zealand rabbits. The degradation process was detected through pocket gas that appeared in hard and soft tissues surrounding in the implanted miniplates and screws. From the changes on the tissues, we can assess the biodegradation process by measuring the gas pocket through micro-CT Scan. Upon the first month of study we euthanized the rabbits and made a micro-CT Scan to see how far the effect of the gas pocket was. Histological analyses were performed to investigate the local tissue response adjacent to the Magnesium ECAP miniplates. We analyzed the femur of a rabbit a month, three months, and five months after implantation. The result showed a degradation rate in the implanted Magnesium ECAP miniplate of 0.61±0.39 mm/year. Unlike the screws, miniplates have higher water content and blood flow than bone, therefore they degrade faster. This study shows promising results for further development of Magnesium ECAP and in the production of osteosynthesis material for rigid fixation in Oral and Maxillofacial skeleton.",
keywords = "Biodegradable, Magnesium ECAP, Micro-CT Scan, Miniplate",
author = "Siska Wiwanto and Sulistyani, {Lilies Dwi} and Latief, {Fourier Dzar Eljabbar} and Sugeng Supriadi and Priosoeryanto, {Bambang Pontjo} and Latief, {Benny Sjarief Sjah}",
note = "Publisher Copyright: {\textcopyright} 2018 Author(s). Published by AIP Publishing.; 2nd Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2017 ; Conference date: 25-07-2017 Through 26-07-2017",
year = "2018",
month = feb,
day = "13",
doi = "10.1063/1.5023947",
language = "English",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
editor = "Radon Dhelika and Yudan Whulanza and Ghiska Ramahdita and Wulan, {Praswasti P.D.K.}",
booktitle = "2nd Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, and Medical Devices",
address = "United States",
}