TY - JOUR
T1 - The Ethanolic Extract of Rhinachantus nasutus (L.) Kurz Flower has Antioxidant, Anti-Gout, and Antibacterial Potential
AU - Irawan, Candra
AU - Elya, Berna
AU - Hanafi, Muhammad
AU - Saputri, Fadlina Chany
N1 - Funding Information:
This research was made possible by a Doctoral Dissertation Research Grant 2022 from the Ministry of Research and Technology of Indonesia and the National Research and Innovation Agency of Indonesia [Nomor: 021/E5/PG.02.00.PT/2022 and 142./PKS/WRIII-DRP/UI/2022 and NKB-782/UN2.RST/HKP.05.00/2022].
Publisher Copyright:
© 2022 Phcogj.Com.
PY - 2022/11
Y1 - 2022/11
N2 - The goal of this research was to explore the potential of Rhinachantus nasutus (L.) Kurz (RnLK) flower extract as an antioxidant utilizing the ferric reducing antioxidant power (FRAP) method; the possibility that it might be used as a treatment for gout by employing the 2,4,6-tribromo-3-hydroxybenzoic acid (TBHBA) technique, as well as the possibility that it could be used as an antibacterial agent against E. coli and B. subtilis. Results: The IC50 value for the extract's ability to serve as an antioxidant is 8.62±0.006 mg/L, indicating that it is quite effective. In addition, the extract of ethanol possesses highly potent anti-gout properties, being capable of bringing about a 81.95±0.1% reduction in uric acid levels. In spite of this, the antibacterial properties of E. coli as well as B. subtilis bacteria were not particularly robust. Conclusion: The RnLK flower has the potential to produce alternative chemicals with the ability to reduce blood uric acid levels, but according to the results of the test, the antibacterial activity has little impact on E. coli and B. subtilis.
AB - The goal of this research was to explore the potential of Rhinachantus nasutus (L.) Kurz (RnLK) flower extract as an antioxidant utilizing the ferric reducing antioxidant power (FRAP) method; the possibility that it might be used as a treatment for gout by employing the 2,4,6-tribromo-3-hydroxybenzoic acid (TBHBA) technique, as well as the possibility that it could be used as an antibacterial agent against E. coli and B. subtilis. Results: The IC50 value for the extract's ability to serve as an antioxidant is 8.62±0.006 mg/L, indicating that it is quite effective. In addition, the extract of ethanol possesses highly potent anti-gout properties, being capable of bringing about a 81.95±0.1% reduction in uric acid levels. In spite of this, the antibacterial properties of E. coli as well as B. subtilis bacteria were not particularly robust. Conclusion: The RnLK flower has the potential to produce alternative chemicals with the ability to reduce blood uric acid levels, but according to the results of the test, the antibacterial activity has little impact on E. coli and B. subtilis.
KW - Antibacterial
KW - FRAP
KW - RnLK
KW - TBHBA
UR - http://www.scopus.com/inward/record.url?scp=85159804931&partnerID=8YFLogxK
U2 - 10.5530/pj.2022.14.181
DO - 10.5530/pj.2022.14.181
M3 - Article
AN - SCOPUS:85159804931
SN - 0975-3575
VL - 14
SP - 867
EP - 872
JO - Pharmacognosy Journal
JF - Pharmacognosy Journal
IS - 6
ER -