The effects of the fortificant NaFeEDTA in tofu flour on red blood cell counts in male Sprague-Dawley rats (Rattus norvegicus L.) were examined. In total, 25 rats were divided into five groups as follows: normal control (NC), which was administered 0.5 % carboxymethyl cellulose (CMC); treatment control (TC), which was administered 0.5 % CMC and unfortified tofu flour; and three treatment groups, which were administered 0.5 % CMC and tofu flour containing 2.7 (T1), 5.4 (T2), or 10.8 mg Fe/kg bw NaFeEDTA (T3). All five groups were treated for 14 consecutive days. Red blood cell counts were measured using an automatic hematology analyzer (Nihon Kohden Celltac α MEK-6450). One-way ANOVA revealed significant effects (P < 0.05) of NaFeEDTA on red blood cell counts in all treatment groups. A least significant difference test illustrated that the red blood cell count was significantly higher (P < 0.05) in the three treatment groups than in the NC and TC groups. The largest increase of the red blood cell count was detected in the T2 group at t14, and the change reflected increases of 22.26 % versus the NC group and 20.24 % versus the TC group.
|Journal||IOP Conference Series: Earth and Environmental Science|
|Publication status||Published - 27 Apr 2020|
|Event||Life and Environmental Sciences Academics Forum 2018, LEAF 2018 - Depok, West Java, Indonesia|
Duration: 1 Nov 2018 → …
- fortificant effect
- red blood cell
- sprague-dawley rats