TY - JOUR
T1 - The effectiveness of oral propranolol for infantile hemangioma on the head and neck region
T2 - A case series
AU - Kreshanti, Prasetyanugraheni
AU - Martin, Valencia Jane
AU - Sukasah, Chaula Luthfia
AU - Nandya Titania, Putri
N1 - Funding Information:
This manuscript received funding from Universitas Indonesia through PUTI Grant with contract number NKB-5/UN2.RST/HKP.05.00/2020 .
Publisher Copyright:
© 2021 The Authors
PY - 2021/7
Y1 - 2021/7
N2 - Introduction: Infantile hemangioma is the most common tumor in infancy, with 60% occurring on the face and neck. A large tumor involving the facial region will cause significant aesthetic and functional impairment and isn't always easy to treat surgically. A non-invasive treatment is needed for this condition. Propranolol has recently been used as a choice of treatment in infantile hemangioma. Presentation of case: We presented two cases of large problematic infantile hemangioma that were successfully managed with oral propranolol. Discussion: Large problematic lesions that ulcerate and bleed often need surgery; however, a substantial defect resulting from surgery is tricky to reconstruct and can cause significant scar. Propranolol is used because of its efficacy and low risk characteristics. Conclusion: Propranolol is an effective treatment to reduce the need of surgical intervention in problematic hemangioma.
AB - Introduction: Infantile hemangioma is the most common tumor in infancy, with 60% occurring on the face and neck. A large tumor involving the facial region will cause significant aesthetic and functional impairment and isn't always easy to treat surgically. A non-invasive treatment is needed for this condition. Propranolol has recently been used as a choice of treatment in infantile hemangioma. Presentation of case: We presented two cases of large problematic infantile hemangioma that were successfully managed with oral propranolol. Discussion: Large problematic lesions that ulcerate and bleed often need surgery; however, a substantial defect resulting from surgery is tricky to reconstruct and can cause significant scar. Propranolol is used because of its efficacy and low risk characteristics. Conclusion: Propranolol is an effective treatment to reduce the need of surgical intervention in problematic hemangioma.
KW - Case report
KW - Infantile hemangioma
KW - Propranolol
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=85109354279&partnerID=8YFLogxK
U2 - 10.1016/j.ijscr.2021.106120
DO - 10.1016/j.ijscr.2021.106120
M3 - Short survey
AN - SCOPUS:85109354279
SN - 2210-2612
VL - 84
JO - International Journal of Surgery Case Reports
JF - International Journal of Surgery Case Reports
M1 - 106120
ER -