The effect of tobacco extracts based biolarvicide emulsion formulation against Aedes aegypti larvae

Yasmin Ekapratiwi, Rachmadiva, Kartini Apriliyana Virgine, Ahmad Fauzantoro, Misri Gozan, Mahdi Jufri

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

5 Citations (Scopus)

Abstract

The tobacco extract has larvicidal activity because it contains nicotine and some toxic compounds. The need to form tobacco extracts in nanoemulsion was due to its smaller particle size, larger surface area, and slow release of active compounds. This study aims to evaluate the effectiveness of tobacco extract nanoemulsion against Aedes aegypti larvae. Nanoemulsion tobacco extract is made by high energy method using ultrasonication with frequency 20kHz for 45 minutes. The tobacco extract was mixed with Tween 20 surfactant with the ratios are 1:0.5, 1:1, and 1:3 (w/w). From the result, bioassay test of larvicidal nanoemulsion with LC 50 was 823.74ppm (F1:0.5), 702.07ppm (F1:1), and 578.48ppm (F1:3), lower than LC 50 of tobacco leaf extract without nanoemulsion 1022.97ppm. The decrease in LC 50 values was directly proportional to the decrease in particle size. The lowest LC 50 values are obtained by the formula F1:3 with an average particle size of 631nm. This study shows that even if the nanoemulsion was not achieved, the emulsion of tobacco extract is potential to control the Aedes aegypti mosquito larvae effectively, due to lower than 750ppm LC50 for (F1:1 and F1:3, 24hr).

Original languageEnglish
Title of host publication3rd Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
Subtitle of host publicationProceedings of the International Symposium of Biomedical Engineering, ISBE 2018
EditorsPraswasti P.D.K. Wulan, Misri Gozan, Sotya Astutiningsih, Ghiska Ramahdita, Radon Dhelika, Prasetyanugraheni Kreshanti
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735418226
DOIs
Publication statusPublished - 9 Apr 2019
Event3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018 - Jakarta, Indonesia
Duration: 6 Aug 20188 Aug 2018

Publication series

NameAIP Conference Proceedings
Volume2092
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018
CountryIndonesia
CityJakarta
Period6/08/188/08/18

Keywords

  • Aedes aegypti
  • biolarvicide
  • extract
  • Nicotiana tabaccum L.
  • tobacco

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