TY - GEN
T1 - The effect of tobacco extracts based biolarvicide emulsion formulation against Aedes aegypti larvae
AU - Ekapratiwi, Yasmin
AU - Rachmadiva,
AU - Virgine, Kartini Apriliyana
AU - Fauzantoro, Ahmad
AU - Gozan, Misri
AU - Jufri, Mahdi
N1 - Publisher Copyright:
© 2019 Author(s).
PY - 2019/4/9
Y1 - 2019/4/9
N2 -
The tobacco extract has larvicidal activity because it contains nicotine and some toxic compounds. The need to form tobacco extracts in nanoemulsion was due to its smaller particle size, larger surface area, and slow release of active compounds. This study aims to evaluate the effectiveness of tobacco extract nanoemulsion against Aedes aegypti larvae. Nanoemulsion tobacco extract is made by high energy method using ultrasonication with frequency 20kHz for 45 minutes. The tobacco extract was mixed with Tween 20 surfactant with the ratios are 1:0.5, 1:1, and 1:3 (w/w). From the result, bioassay test of larvicidal nanoemulsion with LC
50
was 823.74ppm (F1:0.5), 702.07ppm (F1:1), and 578.48ppm (F1:3), lower than LC
50
of tobacco leaf extract without nanoemulsion 1022.97ppm. The decrease in LC
50
values was directly proportional to the decrease in particle size. The lowest LC
50
values are obtained by the formula F1:3 with an average particle size of 631nm. This study shows that even if the nanoemulsion was not achieved, the emulsion of tobacco extract is potential to control the Aedes aegypti mosquito larvae effectively, due to lower than 750ppm LC50 for (F1:1 and F1:3, 24hr).
AB -
The tobacco extract has larvicidal activity because it contains nicotine and some toxic compounds. The need to form tobacco extracts in nanoemulsion was due to its smaller particle size, larger surface area, and slow release of active compounds. This study aims to evaluate the effectiveness of tobacco extract nanoemulsion against Aedes aegypti larvae. Nanoemulsion tobacco extract is made by high energy method using ultrasonication with frequency 20kHz for 45 minutes. The tobacco extract was mixed with Tween 20 surfactant with the ratios are 1:0.5, 1:1, and 1:3 (w/w). From the result, bioassay test of larvicidal nanoemulsion with LC
50
was 823.74ppm (F1:0.5), 702.07ppm (F1:1), and 578.48ppm (F1:3), lower than LC
50
of tobacco leaf extract without nanoemulsion 1022.97ppm. The decrease in LC
50
values was directly proportional to the decrease in particle size. The lowest LC
50
values are obtained by the formula F1:3 with an average particle size of 631nm. This study shows that even if the nanoemulsion was not achieved, the emulsion of tobacco extract is potential to control the Aedes aegypti mosquito larvae effectively, due to lower than 750ppm LC50 for (F1:1 and F1:3, 24hr).
KW - Aedes aegypti
KW - biolarvicide
KW - extract
KW - Nicotiana tabaccum L.
KW - tobacco
UR - http://www.scopus.com/inward/record.url?scp=85064821532&partnerID=8YFLogxK
U2 - 10.1063/1.5096713
DO - 10.1063/1.5096713
M3 - Conference contribution
AN - SCOPUS:85064821532
T3 - AIP Conference Proceedings
BT - 3rd Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
A2 - Wulan, Praswasti P.D.K.
A2 - Gozan, Misri
A2 - Astutiningsih, Sotya
A2 - Ramahdita, Ghiska
A2 - Dhelika, Radon
A2 - Kreshanti, Prasetyanugraheni
PB - American Institute of Physics Inc.
T2 - 3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018
Y2 - 6 August 2018 through 8 August 2018
ER -