The correlation between high sensitivity C-reactive protein level and the extent of coronary lesion and cardiac systolic function in coronary heart disease

Miftah Suryadipradja, Sally Aman Nasution, Dasnan Ismail, Yoga Iwanoff Kasjmir

Research output: Contribution to journalArticlepeer-review

Abstract

To determine the mean value of high sensitivity C-Reactive Protein (hs-CRP), association between plasma level of hs-CRP with extent of disease and systolic function. A cross sectional study had been conducted to 106 coronary artery disease patients (90 stable angina pectoris, 11 unstable angina pectoris and 5 acute myocardial infarction). Plasma quantitative level of hs-CRP with cor angiography to determine extent of disease and ejection fraction were measured. The mean of hs-CRP levels in patients with SVD were 5,5 ± 7,6 mg/L, DVD were 6,6 ± 21,7 mg/L and TVD were 5,5 ± 8,0 mg/L and p=0,056, respectively. There were no significant association between hs- CRP levels with extent of disease. Systolic function had negative correlation with levels of hs-CRP (p=0,015, r=-0,235). This study showed that plasma level of hs-CRP cannot reflect the extent of disease, and it had negative correlation with systolic function.

Original languageEnglish
Pages (from-to)201-206
Number of pages6
JournalMedical Journal of Indonesia
Volume12
Issue number4
DOIs
Publication statusPublished - 1 Oct 2003

Keywords

  • Coronary artery diseases
  • Extent of disease
  • High sensitivity C-Reactive Protein
  • Systolic function

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