The comparison of configuration, degree and sites of obstruction in patients with sleep disordered breathing: Examination using drug-induced sleep endoscopy, Mueller Maneuver and Polysomnography

Niken Ageng Rizki, Susyana Tamin, Fauziah Fardizza, Retno S. Wardani, Arief Marsaban, Saptawati Bardosono, Elvie Zulka Kautzia Rachmawati

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: The purpose of this study is to evaluate the location, configuration, and degree of differences in upper airway obstruction between the Mueller Maneuver (MM) and Drug-induced sleep endoscopy (DISE), thus acquiring a better diagnostic value for SDB patients. Methods: A cross-sectional and analytical descriptive study using retrospective secondary data to evaluate the location, configuration and degree of upper airway obstruction in SDB subjects using the Mueller Maneuver and DISE. Polysomnography (PSG) type 2 was used to determine the SDB degree. Results: Subjects with SDB non-Obstructive sleep apnea (OSA) and OSA show a multilevel obstruction with a different location and configuration due to the various risk factors, such as nasal congestion, laryngopharyngeal reflux, obesity and menopause. Conclusion: Statistical differences in upper airway obstruction configuration between MM and DISE were found in the level of the velum (p=0,036), oropharynx (p<0,001) and epiglottis (p=0,036) and were also found in the obstruction degree of the velum, oropharynx, tongue base and epiglottis with p=0,002; p<0,001; p<0,001 and p<0,001. No statistical difference was found on the lowest oxygen saturation between PSG and DISE (p=0,055).

Original languageEnglish
Pages (from-to)54-57
Number of pages4
JournalInternational Journal of Applied Pharmaceutics
Volume12
Issue numberSpecial Issue 3
DOIs
Publication statusPublished - 2020

Keywords

  • Drug-induced sleep endoscopy (DISE)
  • Mueller maneuver
  • Obstructive sleep apnea (OSA)
  • Polysomnography
  • Sleep disordered breathing (SDB)

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