The comparison effect of CPP-ACP containing propolis and CPP-ACP without propolis on the number of Streptococcus mutans in white-spot enamel surface

Risqa Rina Darwita, Kevin Setijono, Peter Andreas, Gita Arrifa Sjarkawi, Sri Angky Soekanto, Muhamad Sahlan

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Background: The use of CPP-ACP combined with antibacterial propolis agents has not been widely observed and developed. Objective: To compare the effect of CPP-ACP containing propolis and CPP-ACP without propolis on the number of Streptococcus mutans in white-spot enamel surfaces of children aged 7 to 9 years old. Method: Design study was quasi-experimental using one group pretest-posttest design. The subjects were 32 students age 7-9 year old who had white-spot in enamel surfaces were divided into two groups. The two young dentists as examiner were calibrated by Kappa result was 0.82. Both groups carried out baseline on the variable number of S. mutans, which then one group was applied with CPP-ACP propolis paste and other group was applied with CPP-ACP without propolis every day for 4 weeks, then finally, data collection was carried out afterwards, the differences effect were statistically analyzed with T-Test and Wilcoxon. Results: There was a significant decrease (28% from applied CPP-ACP propolis, and 26% applied CPP-ACP without propolis) in the number of S. mutans from each treatment group (p < 0.05). However, there was no significant difference of effect CPP-ACP propolis compared to effect CPP-ACP without propolis in decreasing the number of Streptococcus mutan (p > 0.05). Conclusion: CPP-ACP containing propolis is not proven to be better than CPP-ACP without propolis in the decreasing number of Streptococcus mutans, yet it has the potential to be used as an alternative preventive material that could prevent demineralization and improve remineralization of white-spot in enamel surfaces.

Original languageEnglish
Title of host publication4th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices
Subtitle of host publicationProceedings of the International Symposium of Biomedical Engineering, ISBE 2019
EditorsKenny Lischer, Tomy Abuzairi, Siti Fauziyah Rahman, Misri Gozan
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735419445
DOIs
Publication statusPublished - 10 Dec 2019
Event4th International Symposium of Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices, ISBE 2019 - Padang, West Sumatera, Indonesia
Duration: 22 Jul 201924 Jul 2019

Publication series

NameAIP Conference Proceedings
Volume2193
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference4th International Symposium of Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices, ISBE 2019
Country/TerritoryIndonesia
CityPadang, West Sumatera
Period22/07/1924/07/19

Keywords

  • CPP-ACP
  • remineralization
  • Streptococcus mutans
  • white-spot, propolis

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