TY - JOUR
T1 - The Community Assessment of Psychic Experiences
T2 - Optimal cut-off scores for detecting individuals with a psychotic disorder
AU - Jaya, Edo S.
AU - van Amelsvoort, Therese
AU - Bartels-Velthuis, Agna A.
AU - Bruggeman, Richard
AU - Cahn, Wiepke
AU - de Haan, Lieuwe
AU - Kahn, Rene S.
AU - van Os, Jim
AU - Schirmbeck, Frederike
AU - Simons, Claudia J.P.
AU - Lincoln, Tania M.
N1 - Funding Information:
Edo S. Jaya was supported by Universitas Indonesia's internal research grants (“Hibah Publikasi Artikel di Jurnal Internasional Kuartil Q1 dan Q2 Tahun Anggaran 2019”, Grant No: NKB‐0281/UN2.R3.1/HKP.05.00/2019 and PINTER‐MIDI).
Funding Information:
The infrastructure for the GROUP study is funded through the Geestkracht programme of the Dutch Health Research Council (Zon‐Mw, grant number 10‐000‐1001), and matching funds from participating pharmaceutical companies (Lundbeck, AstraZeneca, Eli Lilly, Janssen Cilag) and universities and mental health care organizations (Amsterdam: Academic Psychiatric Centre of the Academic Medical Center and the mental health institutions: GGZ Ingeest, Arkin, Dijk en Duin, GGZ Rivierduinen, Erasmus Medical Centre, GGZ Noord Holland Noord. Groningen: University Medical Center Groningen and the mental health institutions: Lentis, GGZ Friesland, GGZ Drenthe, Dimence, Mediant, GGNet Warnsveld, Yulius Dordrecht and Parnassia psycho‐medical center The Hague. Maastricht: Maastricht University Medical Centre and the mental health institutions: GGzE, GGZ Breburg, GGZ Oost‐Brabant, Vincent van Gogh voor Geestelijke Gezondheid, Mondriaan, Virenze riagg, Zuyderland GGZ, MET ggz, Universitair Centrum Sint‐Jozef Kortenberg, CAPRI University of Antwerp, PC Ziekeren Sint‐Truiden, PZ Sancta Maria Sint‐Truiden, GGZ Overpelt, OPZ Rekem. Utrecht: University Medical Center Utrecht and the mental health institutions Altrecht, GGZ Centraal and Delta).
Publisher Copyright:
© 2021 The Authors. International Journal of Methods in Psychiatric Research published by John Wiley & Sons Ltd.
PY - 2021/12
Y1 - 2021/12
N2 - Objectives: The need for a brief screening tool for psychosis is widely recognized. The Community Assessment of Psychic Experiences (CAPE) is a popular self-report measure of psychosis, but a cut-off score that can detect those most likely to fulfill diagnostic criteria for psychotic disorder is not established. Methods: A case–control sample from the Genetic Risk and Outcome of Psychosis Project study (N = 1375, healthy individuals, n = 507, and individuals with a psychotic disorder, n = 868), was used to examine cut-off scores of the CAPE with receiver operating curve analyses. We examined 27 possible cut-off scores computed from a combination of scores from the frequency and distress scales of the various factors of the CAPE. Results: The weighted severity positive symptom dimension was most optimal in detecting individuals with a psychotic disorder (>1.75 cut-off; area under the curve = 0.88; sensitivity, 75%; specificity, 88%), which correctly identified 80% of the sample as cases or controls with a diagnostic odds ratio of 22.69. Conclusions: The CAPE can be used as a first screening tool to detect individuals who are likely to fulfill criteria for a psychotic disorder. The >1.75 cut-off of the weighted severity positive symptom dimension provides a better prediction than all alternatives tested so far.
AB - Objectives: The need for a brief screening tool for psychosis is widely recognized. The Community Assessment of Psychic Experiences (CAPE) is a popular self-report measure of psychosis, but a cut-off score that can detect those most likely to fulfill diagnostic criteria for psychotic disorder is not established. Methods: A case–control sample from the Genetic Risk and Outcome of Psychosis Project study (N = 1375, healthy individuals, n = 507, and individuals with a psychotic disorder, n = 868), was used to examine cut-off scores of the CAPE with receiver operating curve analyses. We examined 27 possible cut-off scores computed from a combination of scores from the frequency and distress scales of the various factors of the CAPE. Results: The weighted severity positive symptom dimension was most optimal in detecting individuals with a psychotic disorder (>1.75 cut-off; area under the curve = 0.88; sensitivity, 75%; specificity, 88%), which correctly identified 80% of the sample as cases or controls with a diagnostic odds ratio of 22.69. Conclusions: The CAPE can be used as a first screening tool to detect individuals who are likely to fulfill criteria for a psychotic disorder. The >1.75 cut-off of the weighted severity positive symptom dimension provides a better prediction than all alternatives tested so far.
KW - early detection
KW - psychotic experiences
KW - psychotic symptoms
KW - ROC
KW - schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=85113913456&partnerID=8YFLogxK
U2 - 10.1002/mpr.1893
DO - 10.1002/mpr.1893
M3 - Article
AN - SCOPUS:85113913456
SN - 1049-8931
VL - 30
JO - International Journal of Methods in Psychiatric Research
JF - International Journal of Methods in Psychiatric Research
IS - 4
M1 - e1893
ER -