A personal health record (PHR) is a type of health record maintained by patients. Integrated PHR is an ideal type of PHR that can empower patients to manage their health care and provide continuous connections between patients and their health providers. However, little is known about the adoption of integrated PHR in Indonesia. Thus, this study aims to discuss the challenges in the adoption of integrated PHR in Indonesia from the perspective of regulators as health policymakers in Indonesia. Data collection was conducted using semi-structured interviews with participants from the Ministry of Health and Social Health Insurance Administration Body (BPJS Kesehatan). This qualitative study identified nine challenges in the adoption of integrated PHR in Indonesia. Four challenges are related to technological issues, such as lack of interoperability, unequal distribution of infrastructure, security concerns, and system quality. Five challenges are related to people and organization, such as lack of IT human resources, health professionals' resistance to health information systems, top management support, strategic government plans, and policy changes.