The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease

Mohammed Eslam; Jian Gao Fan; Ming Lung Yu; Vincent Wai Sun Wong; Ian Homer Cua; Chun Jen Liu; Tawesak Tanwandee; Rino Gani; Wai Kay Seto; Shahinul Alam; Dan Yock Young; Saeed Hamid; Ming Hua Zheng; Takumi Kawaguchi; Wah Kheong Chan; Diana Payawal; Soek Siam Tan; George Boon bee Goh; Simone I. Strasser; Hang Dao Viet; Jia Horng Kao; Won Kim; Seung Up Kim; Shelley E. Keating; Yusuf Yilmaz; Lubna Kamani; Chia Chi Wang; Yasser Fouad; Zaigham Abbas; Sombat Treeprasertsuk; Kessarin Thanapirom; Mamun Al Mahtab; Undram Lkhagvaa; Oidov Baatarkhuu; Ashok Kumar Choudhury; Catherine A.M. Stedman; Abhijit Chowdhury; A. Kadir Dokmeci; Fu Sheng Wang; Han Chieh Lin; Jee Fu Huang; Jess Howell; Jidong Jia; Mohamed Alboraie; Stuart K. Roberts; Masato Yoneda; Hasmik Ghazinian; Aram Mirijanyan; Yuemin Nan; Cosmas Rinaldi Adithya Lesmana; Leon A. Adams; Gamal Shiha; Manoj Kumar; Necati Örmeci; Lai Wei; George Lau; Masao Omata; Shiv K. Sarin; Jacob George

doi:10.1007/s12072-024-10774-3

The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease

Mohammed Eslam, Jian Gao Fan, Ming Lung Yu, Vincent Wai Sun Wong, Ian Homer Cua, Chun Jen Liu, Tawesak Tanwandee, Rino Gani, Wai Kay Seto, Shahinul Alam, Dan Yock Young, Saeed Hamid, Ming Hua Zheng, Takumi Kawaguchi, Wah Kheong Chan, Diana Payawal, Soek Siam Tan, George Boon bee Goh, Simone I. Strasser, Hang Dao VietJia Horng Kao, Won Kim, Seung Up Kim, Shelley E. Keating, Yusuf Yilmaz, Lubna Kamani, Chia Chi Wang, Yasser Fouad, Zaigham Abbas, Sombat Treeprasertsuk, Kessarin Thanapirom, Mamun Al Mahtab, Undram Lkhagvaa, Oidov Baatarkhuu, Ashok Kumar Choudhury, Catherine A.M. Stedman, Abhijit Chowdhury, A. Kadir Dokmeci, Fu Sheng Wang, Han Chieh Lin, Jee Fu Huang, Jess Howell, Jidong Jia, Mohamed Alboraie, Stuart K. Roberts, Masato Yoneda, Hasmik Ghazinian, Aram Mirijanyan, Yuemin Nan, Cosmas Rinaldi Adithya Lesmana, Leon A. Adams, Gamal Shiha, Manoj Kumar, Necati Örmeci, Lai Wei, George Lau, Masao Omata, Shiv K. Sarin, Jacob George

Department of Internal Medicine

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9 Citations (Scopus)

Abstract

Metabolic dysfunction-associated fatty liver disease (MAFLD) affects over one-fourth of the global adult population and is the leading cause of liver disease worldwide. To address this, the Asian Pacific Association for the Study of the Liver (APASL) has created clinical practice guidelines focused on MAFLD. The guidelines cover various aspects of the disease, such as its epidemiology, diagnosis, screening, assessment, and treatment. The guidelines aim to advance clinical practice, knowledge, and research on MAFLD, particularly in special groups. The guidelines are designed to advance clinical practice, to provide evidence-based recommendations to assist healthcare stakeholders in decision-making and to improve patient care and disease awareness. The guidelines take into account the burden of clinical management for the healthcare sector.

Original language	English
Article number	e070189
Pages (from-to)	261-301
Number of pages	41
Journal	Hepatology International
Volume	19
Issue number	2
DOIs	https://doi.org/10.1007/s12072-024-10774-3
Publication status	Published - Apr 2025

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10.1007/s12072-024-10774-3

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Eslam, M., Fan, J. G., Yu, M. L., Wong, V. W. S., Cua, I. H., Liu, C. J., Tanwandee, T., Gani, R., Seto, W. K., Alam, S., Young, D. Y., Hamid, S., Zheng, M. H., Kawaguchi, T., Chan, W. K., Payawal, D., Tan, S. S., Goh, G. B. B., Strasser, S. I., ... George, J. (2025). The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease. Hepatology International, 19(2), 261-301. Article e070189. https://doi.org/10.1007/s12072-024-10774-3

@article{6dabb85b25394ff79aa31a5052f7754e,

title = "The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease",

abstract = "Metabolic dysfunction-associated fatty liver disease (MAFLD) affects over one-fourth of the global adult population and is the leading cause of liver disease worldwide. To address this, the Asian Pacific Association for the Study of the Liver (APASL) has created clinical practice guidelines focused on MAFLD. The guidelines cover various aspects of the disease, such as its epidemiology, diagnosis, screening, assessment, and treatment. The guidelines aim to advance clinical practice, knowledge, and research on MAFLD, particularly in special groups. The guidelines are designed to advance clinical practice, to provide evidence-based recommendations to assist healthcare stakeholders in decision-making and to improve patient care and disease awareness. The guidelines take into account the burden of clinical management for the healthcare sector.",

author = "Mohammed Eslam and Fan, \{Jian Gao\} and Yu, \{Ming Lung\} and Wong, \{Vincent Wai Sun\} and Cua, \{Ian Homer\} and Liu, \{Chun Jen\} and Tawesak Tanwandee and Rino Gani and Seto, \{Wai Kay\} and Shahinul Alam and Young, \{Dan Yock\} and Saeed Hamid and Zheng, \{Ming Hua\} and Takumi Kawaguchi and Chan, \{Wah Kheong\} and Diana Payawal and Tan, \{Soek Siam\} and Goh, \{George Boon bee\} and Strasser, \{Simone I.\} and Viet, \{Hang Dao\} and Kao, \{Jia Horng\} and Won Kim and Kim, \{Seung Up\} and Keating, \{Shelley E.\} and Yusuf Yilmaz and Lubna Kamani and Wang, \{Chia Chi\} and Yasser Fouad and Zaigham Abbas and Sombat Treeprasertsuk and Kessarin Thanapirom and \{Al Mahtab\}, Mamun and Undram Lkhagvaa and Oidov Baatarkhuu and Choudhury, \{Ashok Kumar\} and Stedman, \{Catherine A.M.\} and Abhijit Chowdhury and Dokmeci, \{A. Kadir\} and Wang, \{Fu Sheng\} and Lin, \{Han Chieh\} and Huang, \{Jee Fu\} and Jess Howell and Jidong Jia and Mohamed Alboraie and Roberts, \{Stuart K.\} and Masato Yoneda and Hasmik Ghazinian and Aram Mirijanyan and Yuemin Nan and Lesmana, \{Cosmas Rinaldi Adithya\} and Adams, \{Leon A.\} and Gamal Shiha and Manoj Kumar and Necati {\"O}rmeci and Lai Wei and George Lau and Masao Omata and Sarin, \{Shiv K.\} and Jacob George",

note = "Publisher Copyright: {\textcopyright} Asian Pacific Association for the Study of the Liver 2025.",

year = "2025",

month = apr,

doi = "10.1007/s12072-024-10774-3",

language = "English",

volume = "19",

pages = "261--301",

journal = "Hepatology International",

issn = "1936-0533",

publisher = "Springer",

number = "2",

}

Eslam, M, Fan, JG, Yu, ML, Wong, VWS, Cua, IH, Liu, CJ, Tanwandee, T, Gani, R, Seto, WK, Alam, S, Young, DY, Hamid, S, Zheng, MH, Kawaguchi, T, Chan, WK, Payawal, D, Tan, SS, Goh, GBB, Strasser, SI, Viet, HD, Kao, JH, Kim, W, Kim, SU, Keating, SE, Yilmaz, Y, Kamani, L, Wang, CC, Fouad, Y, Abbas, Z, Treeprasertsuk, S, Thanapirom, K, Al Mahtab, M, Lkhagvaa, U, Baatarkhuu, O, Choudhury, AK, Stedman, CAM, Chowdhury, A, Dokmeci, AK, Wang, FS, Lin, HC, Huang, JF, Howell, J, Jia, J, Alboraie, M, Roberts, SK, Yoneda, M, Ghazinian, H, Mirijanyan, A, Nan, Y, Lesmana, CRA, Adams, LA, Shiha, G, Kumar, M, Örmeci, N, Wei, L, Lau, G, Omata, M, Sarin, SK & George, J 2025, 'The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease', Hepatology International, vol. 19, no. 2, e070189, pp. 261-301. https://doi.org/10.1007/s12072-024-10774-3

The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease. / Eslam, Mohammed; Fan, Jian Gao; Yu, Ming Lung et al.
In: Hepatology International, Vol. 19, No. 2, e070189, 04.2025, p. 261-301.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease

AU - Eslam, Mohammed

AU - Fan, Jian Gao

AU - Yu, Ming Lung

AU - Wong, Vincent Wai Sun

AU - Cua, Ian Homer

AU - Liu, Chun Jen

AU - Tanwandee, Tawesak

AU - Gani, Rino

AU - Seto, Wai Kay

AU - Alam, Shahinul

AU - Young, Dan Yock

AU - Hamid, Saeed

AU - Zheng, Ming Hua

AU - Kawaguchi, Takumi

AU - Chan, Wah Kheong

AU - Payawal, Diana

AU - Tan, Soek Siam

AU - Goh, George Boon bee

AU - Strasser, Simone I.

AU - Viet, Hang Dao

AU - Kao, Jia Horng

AU - Kim, Won

AU - Kim, Seung Up

AU - Keating, Shelley E.

AU - Yilmaz, Yusuf

AU - Kamani, Lubna

AU - Wang, Chia Chi

AU - Fouad, Yasser

AU - Abbas, Zaigham

AU - Treeprasertsuk, Sombat

AU - Thanapirom, Kessarin

AU - Al Mahtab, Mamun

AU - Lkhagvaa, Undram

AU - Baatarkhuu, Oidov

AU - Choudhury, Ashok Kumar

AU - Stedman, Catherine A.M.

AU - Chowdhury, Abhijit

AU - Dokmeci, A. Kadir

AU - Wang, Fu Sheng

AU - Lin, Han Chieh

AU - Huang, Jee Fu

AU - Howell, Jess

AU - Jia, Jidong

AU - Alboraie, Mohamed

AU - Roberts, Stuart K.

AU - Yoneda, Masato

AU - Ghazinian, Hasmik

AU - Mirijanyan, Aram

AU - Nan, Yuemin

AU - Lesmana, Cosmas Rinaldi Adithya

AU - Adams, Leon A.

AU - Shiha, Gamal

AU - Kumar, Manoj

AU - Örmeci, Necati

AU - Wei, Lai

AU - Lau, George

AU - Omata, Masao

AU - Sarin, Shiv K.

AU - George, Jacob

PY - 2025/4

Y1 - 2025/4

N2 - Metabolic dysfunction-associated fatty liver disease (MAFLD) affects over one-fourth of the global adult population and is the leading cause of liver disease worldwide. To address this, the Asian Pacific Association for the Study of the Liver (APASL) has created clinical practice guidelines focused on MAFLD. The guidelines cover various aspects of the disease, such as its epidemiology, diagnosis, screening, assessment, and treatment. The guidelines aim to advance clinical practice, knowledge, and research on MAFLD, particularly in special groups. The guidelines are designed to advance clinical practice, to provide evidence-based recommendations to assist healthcare stakeholders in decision-making and to improve patient care and disease awareness. The guidelines take into account the burden of clinical management for the healthcare sector.

AB - Metabolic dysfunction-associated fatty liver disease (MAFLD) affects over one-fourth of the global adult population and is the leading cause of liver disease worldwide. To address this, the Asian Pacific Association for the Study of the Liver (APASL) has created clinical practice guidelines focused on MAFLD. The guidelines cover various aspects of the disease, such as its epidemiology, diagnosis, screening, assessment, and treatment. The guidelines aim to advance clinical practice, knowledge, and research on MAFLD, particularly in special groups. The guidelines are designed to advance clinical practice, to provide evidence-based recommendations to assist healthcare stakeholders in decision-making and to improve patient care and disease awareness. The guidelines take into account the burden of clinical management for the healthcare sector.

UR - http://www.scopus.com/inward/record.url?scp=105003176860&partnerID=8YFLogxK

U2 - 10.1007/s12072-024-10774-3

DO - 10.1007/s12072-024-10774-3

M3 - Article

C2 - 40016576

AN - SCOPUS:105003176860

SN - 1936-0533

VL - 19

SP - 261

EP - 301

JO - Hepatology International

JF - Hepatology International

IS - 2

M1 - e070189

ER -

The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease

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