TY - JOUR
T1 - The antimicrobial effect of Limosilactobacillus reuteri as probiotic on oral bacteria
T2 - A scoping review
AU - Ananda, Nissia
AU - Suniarti, Dewi Fatma
AU - Bachtiar, Endang Winiati
N1 - Publisher Copyright:
Copyright: © 2024 Ananda N et al.
PY - 2024
Y1 - 2024
N2 - Dysbiosis among oral microbial community in the oral cavity can lead to several oral diseases. Probiotic therapy is known to correct these imbalances. Limosilactobacillus reuteri is one of the most studied strains of probiotics and can control oral microbiota through reuterin, a wide-spectrum antimicrobial agent. The objective of this review was to evaluate the effect of the antimicrobial activity of Limosilactobacillus reuteri on the oral bacteria of humans. This review used PubMed, Scopus, EMBASE, ScienceDirect, and Google Scholar databases as bibliographic resources. Studies with matching keywords were analyzed and screened with PRISMA-ScR recommendations. Sixteen articles were selected for this review, which included a total of 832 patients. Based on this review, Limosilactobacillus reuteri has a strong antibacterial effect against Streptococcus mutans in healthy individuals but is not effective against Lactobacillus. Additionally, it has a significant antibacterial effect against Porphiromonas gingivalis in patients with periodontitis, although its effectiveness is not stable in patients with peri-implant infections. Furthermore, Limosilactobacillus reuterihas varying results against other bacteria, indicating the need for further extensive research to ensure its efficacy.
AB - Dysbiosis among oral microbial community in the oral cavity can lead to several oral diseases. Probiotic therapy is known to correct these imbalances. Limosilactobacillus reuteri is one of the most studied strains of probiotics and can control oral microbiota through reuterin, a wide-spectrum antimicrobial agent. The objective of this review was to evaluate the effect of the antimicrobial activity of Limosilactobacillus reuteri on the oral bacteria of humans. This review used PubMed, Scopus, EMBASE, ScienceDirect, and Google Scholar databases as bibliographic resources. Studies with matching keywords were analyzed and screened with PRISMA-ScR recommendations. Sixteen articles were selected for this review, which included a total of 832 patients. Based on this review, Limosilactobacillus reuteri has a strong antibacterial effect against Streptococcus mutans in healthy individuals but is not effective against Lactobacillus. Additionally, it has a significant antibacterial effect against Porphiromonas gingivalis in patients with periodontitis, although its effectiveness is not stable in patients with peri-implant infections. Furthermore, Limosilactobacillus reuterihas varying results against other bacteria, indicating the need for further extensive research to ensure its efficacy.
KW - antimicrobial
KW - dentistry
KW - Lactobacillus reuteri
KW - Limosilactobacillus reuteri
KW - oral bacteria
KW - oral microbiome
KW - oral probiotic
UR - http://www.scopus.com/inward/record.url?scp=85186854591&partnerID=8YFLogxK
U2 - 10.12688/f1000research.139697.2
DO - 10.12688/f1000research.139697.2
M3 - Review article
AN - SCOPUS:85186854591
SN - 2046-1402
VL - 12
JO - F1000Research
JF - F1000Research
M1 - 1495
ER -