Tatalaksana non imunosupresan sindrom nefrotik pada anak

Nephrotic syndrome is clinical condition consists of massive proteinuria, hypoalbuminemia (<2,5 g/dL), oedema, andhypercholesterolemia. The main treatment of nephrotic syndrome is steroid. In some conditions, besides steroid, it is used other immunosuppressant. Besides immunosuppressant, supportive management is very important in treatment of nephrotic syndrome, such as dietetic, management of oedema, hypertension, hypovolemia, trombosis, hyperlipidemia, and infection. Dietetic management consist of adequate of calorie, protein according to recommended daily allowance, low saturated, lipid, and salt restriction diet. The compostion of nutrition is 10-14% of protein; 40-50% of poly- and monounsaturated, lipid and 40-50% of carbohydrate. Treatment of oedema consists of ata fluid restriction, diuretics, and albumin infusion if needed. Infection is often happened in nephrotic syndrome, such as selulitis, peritonitis, and pneumonia which treated with antibiotics cefotaxime, ceftriaxonen, co-amoxyclav. Antihypertension for children usually are diuretics, angiotensin converting enzyme inhibitors, angiotensin receptor blockers, calcium channel blockers, alpha-symphatetic agents, beta blockers and vasodilator. Physical activity limitation is unnecessary and the child with mild or not severe oedema allowed go to school.