Talaromyces atroroseus in HIV and non-HIV patient: A first report from Indonesia

Sem Samuel Surja; Robiatul Adawiyah; Jos Houbraken; Anna Rozaliyani; Ridhawati Sjam; Evy Yunihastuti; Retno Wahyuningsih

doi:10.1093/mmy/myz090

Talaromyces atroroseus in HIV and non-HIV patient: A first report from Indonesia

Sem Samuel Surja, Robiatul Adawiyah, Jos Houbraken, Anna Rozaliyani, Ridhawati Sjam, Evy Yunihastuti, Retno Wahyuningsih

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

We performed morphology, molecular study and antifungal susceptibility test on 10 Talaromyces sp. isolates: eight clinical isolates (human immunodeficiency virus (HIV) and non-HIV-patient) and two isolates from rats. All strains produced red soluble pigment and microscopically showed Penicillium-like structure in room temperature and yeast-like structure in 37°C. Based on molecular analysis, nine isolates were identified as Talaromyces atroroseus (including the isolates from rats) and one as T. marneffei. Our susceptibility result of T. marneffei supports the use of amphotericin B, itraconazole for talaromycosis marneffei management. Talaromyces atroroseus showed variable MIC to echinocandin, azole derivatives, 5-flucytosine and amphotericin B.

Original language	English
Pages (from-to)	560-563
Number of pages	4
Journal	Medical Mycology
Volume	58
Issue number	4
DOIs	https://doi.org/10.1093/mmy/myz090
Publication status	Published - 1 Jun 2020

Keywords

BenA
Talaromyces atroroseus
Talaromyces marneffei
Indonesia
ITS

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/mmy/myz090

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title = "Talaromyces atroroseus in HIV and non-HIV patient: A first report from Indonesia",

abstract = "We performed morphology, molecular study and antifungal susceptibility test on 10 Talaromyces sp. isolates: eight clinical isolates (human immunodeficiency virus (HIV) and non-HIV-patient) and two isolates from rats. All strains produced red soluble pigment and microscopically showed Penicillium-like structure in room temperature and yeast-like structure in 37°C. Based on molecular analysis, nine isolates were identified as Talaromyces atroroseus (including the isolates from rats) and one as T. marneffei. Our susceptibility result of T. marneffei supports the use of amphotericin B, itraconazole for talaromycosis marneffei management. Talaromyces atroroseus showed variable MIC to echinocandin, azole derivatives, 5-flucytosine and amphotericin B.",

keywords = "BenA, Talaromyces atroroseus, Talaromyces marneffei, Indonesia, ITS",

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T2 - A first report from Indonesia

AU - Surja, Sem Samuel

AU - Adawiyah, Robiatul

AU - Houbraken, Jos

AU - Rozaliyani, Anna

AU - Sjam, Ridhawati

AU - Yunihastuti, Evy

AU - Wahyuningsih, Retno

N1 - Publisher Copyright: © The Author(s) 2019.

PY - 2020/6/1

Y1 - 2020/6/1

N2 - We performed morphology, molecular study and antifungal susceptibility test on 10 Talaromyces sp. isolates: eight clinical isolates (human immunodeficiency virus (HIV) and non-HIV-patient) and two isolates from rats. All strains produced red soluble pigment and microscopically showed Penicillium-like structure in room temperature and yeast-like structure in 37°C. Based on molecular analysis, nine isolates were identified as Talaromyces atroroseus (including the isolates from rats) and one as T. marneffei. Our susceptibility result of T. marneffei supports the use of amphotericin B, itraconazole for talaromycosis marneffei management. Talaromyces atroroseus showed variable MIC to echinocandin, azole derivatives, 5-flucytosine and amphotericin B.

AB - We performed morphology, molecular study and antifungal susceptibility test on 10 Talaromyces sp. isolates: eight clinical isolates (human immunodeficiency virus (HIV) and non-HIV-patient) and two isolates from rats. All strains produced red soluble pigment and microscopically showed Penicillium-like structure in room temperature and yeast-like structure in 37°C. Based on molecular analysis, nine isolates were identified as Talaromyces atroroseus (including the isolates from rats) and one as T. marneffei. Our susceptibility result of T. marneffei supports the use of amphotericin B, itraconazole for talaromycosis marneffei management. Talaromyces atroroseus showed variable MIC to echinocandin, azole derivatives, 5-flucytosine and amphotericin B.

KW - BenA

KW - Talaromyces atroroseus

KW - Talaromyces marneffei

KW - Indonesia

KW - ITS

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DO - 10.1093/mmy/myz090

M3 - Article

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AN - SCOPUS:85085715396

SN - 1369-3786

VL - 58

SP - 560

EP - 563

JO - Medical Mycology

JF - Medical Mycology

IS - 4

ER -

Talaromyces atroroseus in HIV and non-HIV patient: A first report from Indonesia

Abstract

Keywords

UN SDGs

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