Talaromyces atroroseus in HIV and non-HIV patient: A first report from Indonesia

Sem Samuel Surja, Robiatul Adawiyah, Jos Houbraken, Anna Rozaliyani, Ridhawati Sjam, Evy Yunihastuti, Retno Wahyuningsih

Research output: Contribution to journalArticle

Abstract

We performed morphology, molecular study and antifungal susceptibility test on 10 Talaromyces sp. isolates: eight clinical isolates (human immunodeficiency virus (HIV) and non-HIV-patient) and two isolates from rats. All strains produced red soluble pigment and microscopically showed Penicillium-like structure in room temperature and yeast-like structure in 37°C. Based on molecular analysis, nine isolates were identified as Talaromyces atroroseus (including the isolates from rats) and one as T. marneffei. Our susceptibility result of T. marneffei supports the use of amphotericin B, itraconazole for talaromycosis marneffei management. Talaromyces atroroseus showed variable MIC to echinocandin, azole derivatives, 5-flucytosine and amphotericin B.

Original languageEnglish
Pages (from-to)560-563
Number of pages4
JournalMedical Mycology
Volume58
Issue number4
DOIs
Publication statusPublished - 1 Jun 2020

Keywords

  • BenA
  • Talaromyces atroroseus
  • Talaromyces marneffei
  • Indonesia
  • ITS

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