Hypertension is a condition that is often prevalent and can lead to stroke, kidney failure, and death if not detected early and the treatment is not done properly. Hypertension is an increasing in systolic blood pressure over 140 mmHg and diastolic blood pressure over 90 mmHg. Increased blood pressure that lasts for a long time can cause damage to the kidneys (renal failure), heart (coronary heart disease), and brain (causing a stroke). Many hypertension patients with uncontrolled blood pressure. Based on report of the Indonesian Ministry of Health in 2014 regarding hypertension, nationally 25.8% of Indonesia's population suffer from hypertension. A topic that is being discussed is the M2M services in health sector. Utilization of M2M services in health sector is expected to help or improve existing health services. M2M technology connects machines, devices and equipment through various types of communication. This makes the device into a smart device that can communicate with each other. In this paper, we propose design of M2M communication system that are not only monitor the patient, but also can provide medical recommendations. The treatment can be monitored by doctor. In this system, there will be two devices and a mobile application. The first device is sphygmomanometer connected to the microcontroller, the second device is medicine box connected to the microcontroller, and a mobile application. With the design of the system of machine-to-machine (M2M) that we propose, this system is expected to help hypertension patients on their health recovery.