Synthesis of pyranopyrazole derivative compounds with nano-Fe3O4catalyst

A. H. Cahyana, A. Mufidah

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Pyranopyrazole is a heterocyclic organic compound in which the skeleton is a pyran ring substituted by pyrazole in the ortho position. Pyranopyrazole can be synthesized using aldehyde, hydrazine, ethyl acetoacetate, and malononitrile as precursors with a multicomponent reaction method. Synthesis of pyranopyrazole is carried out through the Knoevenagel condensation reaction, Michael's addition, and cyclization. In this research, nano-Fe3O4 is synthesized from rust and used cooking oil. Synthesis of pyranopyrazole derivate compound reached the optimal condition within 60 min of the reaction with the amount of nano-Fe3O4 catalyst is 1 % (w/w). Benzaldehyde, 2-hydroxybenzaldehyde, and cinnamaldehyde are used in variations of aldehyde in this research. The results show that the reaction in 60 min using nano-Fe3O4 produces pyranopyrazole derivative compounds. The nano-Fe3O4 is characterized using FTIR, XRD, and SEM-EDS instruments. The resulting products are characterized by FTIR, UV-Visible, and GC-MS.

Original languageEnglish
Title of host publicationProceedings of the 6th International Symposium on Current Progress in Mathematics and Sciences 2020, ISCPMS 2020
EditorsTribidasari A. Ivandini, David G. Churchill, Youngil Lee, Yatimah Binti Alias, Chris Margules
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735441132
DOIs
Publication statusPublished - 23 Jul 2021
Event6th International Symposium on Current Progress in Mathematics and Sciences 2020, ISCPMS 2020 - Depok, Indonesia
Duration: 27 Oct 202028 Oct 2020

Publication series

NameAIP Conference Proceedings
Volume2374
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference6th International Symposium on Current Progress in Mathematics and Sciences 2020, ISCPMS 2020
Country/TerritoryIndonesia
CityDepok
Period27/10/2028/10/20

Keywords

  • Cinnamaldehyde
  • Multicomponent reaction
  • Nano-FeO
  • Pyranopyrazole

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