Synthesis of Copper (II) Oxide Nanoparticles using Vitis vinifera L. Leaf Extract and its Application as a Catalyst in Doebner Reaction

Felie Virgayani Kurniawan, Antonius Herry Cahyana, Rika Tri Yunarti

Research output: Contribution to journalArticlepeer-review

Abstract

Plant extracts can be used to synthesize nanoparticle because it is efficient, economical, and friendly to the environment. Copper oxide nanoparticles (CuO NPs) were synthesized using an aqueous fraction of Vitis vinifera L leaf extract and Cu(NO3)2 solution as a precursor. This fraction contains secondary metabolites as a reduction agent and stabilizing agents to formed CuO NPs. CuO NPs can be used as a catalyst in a chemical reaction, one of which is the Doebner reaction, which is a simple and efficient reaction of aniline, aromatic aldehydes, and pyruvic acid under reflux conditions to produce derivatives quinoline-4-carboxylic acid. CuO NPs were effectively used in the Doebner reaction and yielded a product is 79.84%. The CuO NPs characterized by Fourier Transform Infra-Red (FTIR), and X-ray Diffraction (XRD) which showed CuO NPs were formed with a size of 24.39 nm. The product synthesized was characterized by TLC (Thin Layer Chromatography), FTIR, UV-Vis Spectrophotometry, and Liquid Chromatography Mass Spectrometry (LC-MS) and confirmed 2-phenylquinoline-4-carboxylic acid was formed.

Original languageEnglish
Article number8
Pages (from-to)227-234
Number of pages8
JournalMakara Journal of Science
Volume27
Issue number3
DOIs
Publication statusPublished - Sept 2023

Keywords

  • copper (II) oxide nanoparticles
  • doebner reaction
  • plant mediated synthesis
  • quinoline
  • Vitis vinifera L

Fingerprint

Dive into the research topics of 'Synthesis of Copper (II) Oxide Nanoparticles using Vitis vinifera L. Leaf Extract and its Application as a Catalyst in Doebner Reaction'. Together they form a unique fingerprint.

Cite this