Synthesis, characterization, and antibacterial evaluation of curcumin-sulfanilamide compound

Nurjanah Nurjanah; Endang Saepudin

Synthesis, characterization, and antibacterial evaluation of curcumin-sulfanilamide compound

Nurjanah Nurjanah, Endang Saepudin

Department of Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Curcumin, a diarylheptanoids compound which isolated primary from Curcuma longa, exhibits a variety of exciting biological activities, including antibacterial agent. In the present study, a sulfanilamide-contained curcumin compound was synthesized and characterized to evaluated for its antibacterial activity against Gram-positive bacteria S. aureus, B. subtilis and Gram-negative bacteria E. coli. The characterization of the synthesized compound was determined by UV/Vis, FTIR, and MS spectrometers. Curcumin-sulfanilamide compound exhibited the best antibacterial activity against Gram-negative bacteria compared to curcumin and the curcumin-isoxazole with inhibitory zone of 11 mm.

Original language	English
Title of host publication	Symposium of Materials Science and Chemistry II
Editors	Tutik Dwi Wahyuningsih, Roto Roto, Dwi Siswanta, Rohana Adnan, Laurent Commeiras, Kuwat Triyana, Kuwat Triyana, Indriana Kartini, Julius Motuzas
Publisher	Trans Tech Publications Ltd
Pages	265-269
Number of pages	5
ISBN (Print)	9783035716139
Publication status	Published - 1 Jan 2020
Event	5th International Conference on Science and Technology, ICST 2019 - Yogyakarta, Indonesia Duration: 30 Jul 2019 → 31 Jul 2019

Publication series

Name	Key Engineering Materials
Volume	840 KEM
ISSN (Print)	1013-9826
ISSN (Electronic)	1662-9795

Conference

Conference	5th International Conference on Science and Technology, ICST 2019
Country/Territory	Indonesia
City	Yogyakarta
Period	30/07/19 → 31/07/19

Keywords

Antibacterial
Curcumin
Curcumin-isoxazole
Curcumin-sulfanilamide

Cite this

Nurjanah, N., & Saepudin, E. (2020). Synthesis, characterization, and antibacterial evaluation of curcumin-sulfanilamide compound. In T. D. Wahyuningsih, R. Roto, D. Siswanta, R. Adnan, L. Commeiras, K. Triyana, K. Triyana, I. Kartini, & J. Motuzas (Eds.), Symposium of Materials Science and Chemistry II (pp. 265-269). (Key Engineering Materials; Vol. 840 KEM). Trans Tech Publications Ltd.

Nurjanah, Nurjanah ; Saepudin, Endang. / Synthesis, characterization, and antibacterial evaluation of curcumin-sulfanilamide compound. Symposium of Materials Science and Chemistry II. editor / Tutik Dwi Wahyuningsih ; Roto Roto ; Dwi Siswanta ; Rohana Adnan ; Laurent Commeiras ; Kuwat Triyana ; Kuwat Triyana ; Indriana Kartini ; Julius Motuzas. Trans Tech Publications Ltd, 2020. pp. 265-269 (Key Engineering Materials).

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title = "Synthesis, characterization, and antibacterial evaluation of curcumin-sulfanilamide compound",

abstract = "Curcumin, a diarylheptanoids compound which isolated primary from Curcuma longa, exhibits a variety of exciting biological activities, including antibacterial agent. In the present study, a sulfanilamide-contained curcumin compound was synthesized and characterized to evaluated for its antibacterial activity against Gram-positive bacteria S. aureus, B. subtilis and Gram-negative bacteria E. coli. The characterization of the synthesized compound was determined by UV/Vis, FTIR, and MS spectrometers. Curcumin-sulfanilamide compound exhibited the best antibacterial activity against Gram-negative bacteria compared to curcumin and the curcumin-isoxazole with inhibitory zone of 11 mm.",

keywords = "Antibacterial, Curcumin, Curcumin-isoxazole, Curcumin-sulfanilamide",

author = "Nurjanah Nurjanah and Endang Saepudin",

note = "Publisher Copyright: {\textcopyright} 2020 Trans Tech Publications Ltd, Switzerland.; 5th International Conference on Science and Technology, ICST 2019 ; Conference date: 30-07-2019 Through 31-07-2019",

year = "2020",

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language = "English",

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series = "Key Engineering Materials",

publisher = "Trans Tech Publications Ltd",

pages = "265--269",

editor = "Wahyuningsih, {Tutik Dwi} and Roto Roto and Dwi Siswanta and Rohana Adnan and Laurent Commeiras and Kuwat Triyana and Kuwat Triyana and Indriana Kartini and Julius Motuzas",

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Nurjanah, N & Saepudin, E 2020, Synthesis, characterization, and antibacterial evaluation of curcumin-sulfanilamide compound. in TD Wahyuningsih, R Roto, D Siswanta, R Adnan, L Commeiras, K Triyana, K Triyana, I Kartini & J Motuzas (eds), Symposium of Materials Science and Chemistry II. Key Engineering Materials, vol. 840 KEM, Trans Tech Publications Ltd, pp. 265-269, 5th International Conference on Science and Technology, ICST 2019, Yogyakarta, Indonesia, 30/07/19.

Synthesis, characterization, and antibacterial evaluation of curcumin-sulfanilamide compound. / Nurjanah, Nurjanah; Saepudin, Endang.
Symposium of Materials Science and Chemistry II. ed. / Tutik Dwi Wahyuningsih; Roto Roto; Dwi Siswanta; Rohana Adnan; Laurent Commeiras; Kuwat Triyana; Kuwat Triyana; Indriana Kartini; Julius Motuzas. Trans Tech Publications Ltd, 2020. p. 265-269 (Key Engineering Materials; Vol. 840 KEM).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Synthesis, characterization, and antibacterial evaluation of curcumin-sulfanilamide compound

AU - Nurjanah, Nurjanah

AU - Saepudin, Endang

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Curcumin, a diarylheptanoids compound which isolated primary from Curcuma longa, exhibits a variety of exciting biological activities, including antibacterial agent. In the present study, a sulfanilamide-contained curcumin compound was synthesized and characterized to evaluated for its antibacterial activity against Gram-positive bacteria S. aureus, B. subtilis and Gram-negative bacteria E. coli. The characterization of the synthesized compound was determined by UV/Vis, FTIR, and MS spectrometers. Curcumin-sulfanilamide compound exhibited the best antibacterial activity against Gram-negative bacteria compared to curcumin and the curcumin-isoxazole with inhibitory zone of 11 mm.

AB - Curcumin, a diarylheptanoids compound which isolated primary from Curcuma longa, exhibits a variety of exciting biological activities, including antibacterial agent. In the present study, a sulfanilamide-contained curcumin compound was synthesized and characterized to evaluated for its antibacterial activity against Gram-positive bacteria S. aureus, B. subtilis and Gram-negative bacteria E. coli. The characterization of the synthesized compound was determined by UV/Vis, FTIR, and MS spectrometers. Curcumin-sulfanilamide compound exhibited the best antibacterial activity against Gram-negative bacteria compared to curcumin and the curcumin-isoxazole with inhibitory zone of 11 mm.

KW - Antibacterial

KW - Curcumin

KW - Curcumin-isoxazole

KW - Curcumin-sulfanilamide

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M3 - Conference contribution

AN - SCOPUS:85085219034

SN - 9783035716139

T3 - Key Engineering Materials

SP - 265

EP - 269

BT - Symposium of Materials Science and Chemistry II

A2 - Wahyuningsih, Tutik Dwi

A2 - Roto, Roto

A2 - Siswanta, Dwi

A2 - Adnan, Rohana

A2 - Commeiras, Laurent

A2 - Triyana, Kuwat

A2 - Kartini, Indriana

A2 - Motuzas, Julius

PB - Trans Tech Publications Ltd

T2 - 5th International Conference on Science and Technology, ICST 2019

Y2 - 30 July 2019 through 31 July 2019

ER -

Synthesis, characterization, and antibacterial evaluation of curcumin-sulfanilamide compound

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Publication series

Conference

Keywords

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