Synthesis, characterization, and antibacterial evaluation of curcumin-sulfanilamide compound

Nurjanah Nurjanah, Endang Saepudin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Curcumin, a diarylheptanoids compound which isolated primary from Curcuma longa, exhibits a variety of exciting biological activities, including antibacterial agent. In the present study, a sulfanilamide-contained curcumin compound was synthesized and characterized to evaluated for its antibacterial activity against Gram-positive bacteria S. aureus, B. subtilis and Gram-negative bacteria E. coli. The characterization of the synthesized compound was determined by UV/Vis, FTIR, and MS spectrometers. Curcumin-sulfanilamide compound exhibited the best antibacterial activity against Gram-negative bacteria compared to curcumin and the curcumin-isoxazole with inhibitory zone of 11 mm.

Original languageEnglish
Title of host publicationSymposium of Materials Science and Chemistry II
EditorsTutik Dwi Wahyuningsih, Roto Roto, Dwi Siswanta, Rohana Adnan, Laurent Commeiras, Kuwat Triyana, Kuwat Triyana, Indriana Kartini, Julius Motuzas
PublisherTrans Tech Publications Ltd
Pages265-269
Number of pages5
ISBN (Print)9783035716139
Publication statusPublished - 1 Jan 2020
Event5th International Conference on Science and Technology, ICST 2019 - Yogyakarta, Indonesia
Duration: 30 Jul 201931 Jul 2019

Publication series

NameKey Engineering Materials
Volume840 KEM
ISSN (Print)1013-9826
ISSN (Electronic)1662-9795

Conference

Conference5th International Conference on Science and Technology, ICST 2019
CountryIndonesia
CityYogyakarta
Period30/07/1931/07/19

Keywords

  • Antibacterial
  • Curcumin
  • Curcumin-isoxazole
  • Curcumin-sulfanilamide

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  • Cite this

    Nurjanah, N., & Saepudin, E. (2020). Synthesis, characterization, and antibacterial evaluation of curcumin-sulfanilamide compound. In T. D. Wahyuningsih, R. Roto, D. Siswanta, R. Adnan, L. Commeiras, K. Triyana, K. Triyana, I. Kartini, & J. Motuzas (Eds.), Symposium of Materials Science and Chemistry II (pp. 265-269). (Key Engineering Materials; Vol. 840 KEM). Trans Tech Publications Ltd.