Synthesis and antibacterial activity of 2-((1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)ethyl acetate

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Abstract

Derivatization of lawsone compound (1) was done by reacting it with ethanolamine to give 2-((2-hydroxyethyl)amino)-1,4-naphthoquinone (2), and then treating with acetic anhydride to produce the desired compound 2-((1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino) ethyl acetate (3). The target compound possesses the antibacterial activity against E. coli and S. aureus.

Original languageEnglish
Article number012011
JournalIOP Conference Series: Materials Science and Engineering
Volume763
Issue number1
DOIs
Publication statusPublished - 28 Apr 2020
Event3rd International Symposium on Current Progress in Functional Materials 2018, ISCPFM 2018 - Depok, Indonesia
Duration: 8 Aug 20189 Aug 2018

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