Studies on the constituents of fruits of Helicteres isora L.

Toshiko Satake, Kohei Kamiya, Yasuhisa Saiki, Takao Hama, Yasuo Fujimoto, Susumu Kitanaka, Yumiko Kimura, Jun Uzawa, Endang Hanani, Umar Mansur

Research output: Contribution to journalArticlepeer-review

48 Citations (Scopus)

Abstract

Three new compounds; 4'-O-β-D-glucopyranosyl rosmarinic acid (2), 4,4'- O-di-β-D-glucopyranosyl rosmarinic acid(3) and 2R-O-(4'-O-β-D- glucopyranosyl caffeoyl)-3-(4-hydroxyphenyl) lactic acid named as 4'-O-β-D- glucopyranosyl isorinic acid (4) were isolated together with rosmarinic acid (1) from the fruit of Helicteres isora L. (Sterculiaceae), an Indonesian medicinal plant. The structures of these compounds, including the absolute stereochemistry of 4, were elucidated by spectroscopic analysis and chemical means. Compound 3 had greater scavenging activity against superoxide anion produced with xanthine and xanthine oxidase (XOD) than rosmarinic acid (1).

Original languageEnglish
Pages (from-to)1444-1447
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume47
Issue number10
Publication statusPublished - 1 Oct 1999

Keywords

  • Helicteres isora
  • Isorinic acid
  • Rosmarinic acid
  • Rosmarinic acid glycoside
  • Sterculiaceae

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